Is parathyroid hormone a therapeutic option for osteoporosis? A review of the clinical evidence

被引：77

作者：

Cosman, F ^{[1
]}

Lindsay, R

机构：

[1] Helen Hayes Hosp, Reg Bone Ctr, Clin Res Ctr, W Haverstraw, NY 10993 USA

[2] Columbia Presbyterian Med Ctr, Dept Med, New York, NY 10032 USA

来源：

CALCIFIED TISSUE INTERNATIONAL | 1998年 / 62卷 / 06期

关键词：

hormone replacement therapy; estrogen; salmon calcitonin; alendronate; bone turnover;

D O I：

10.1007/s002239900464

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Most of the data on the anabolic effect of PTH have been obtained with hPTH(1-34). Studies have shown a marked increment in spinal bone mass. Most recently we have shown that PTH and estrogen can be given together where there is increased total bone mineral and no loss of bone at any skeletal site. We have also shown the first reduction in vertebral deformity incidence due to PTH treatment.

引用

页码：475 / 480

页数：6

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