Fourier-domain low-coherence interferometry for light-scattering spectroscopy

被引：80
|
作者：
Wax, A [1 ]
Yang, CH
Izatt, JA
机构：
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
[2] Duke Univ, Fitzpatrick Ctr Photon, Durham, NC 27708 USA
来源：
OPTICS LETTERS | 2003年 / 28卷 / 14期
关键词：
D O I：
10.1364/OL.28.001230
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We present a novel method for obtaining depth-resolved spectra for determining scatterer size through elastic-scattering properties. Depth resolution is achieved with a white-light source in a Michelson interferometer with the mixed signal and reference fields dispersed by a spectrograph. The spectrum is Fourier transformed to yield the axial spatial cross correlation between the signal and reference fields with near 1-mum depth resolution. Spectral information is obtained by windowing to yield the scattering amplitude as a function of wave number. The technique is demonstrated by determination of the size of polystyrene microspheres in a subsurface layer with subwavelength accuracy. Application of the technique to probing the size of cell nuclei in living epithelial tissues is discussed. (C) 2003 Optical Society of America.
引用
收藏
页码：1230 / 1232
页数：3
相关论文
共 50 条
  • [1] Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry
    Robles, Francisco E.
    Wax, Adam
    OPTICS LETTERS, 2010, 35 (03) : 360 - 362
  • [2] Fourier-domain angle-resolved low coherence interferometry through an endoscopic fiber bundle for light-scattering spectroscopy
    Pyhtila, JW
    Boyer, JD
    Chalut, KJ
    Wax, A
    OPTICS LETTERS, 2006, 31 (06) : 772 - 774
  • [3] Measurement of angular distributions by use of low-coherence interferometry for light-scattering spectroscopy
    Wax, A
    Yang, CH
    Dasari, RR
    Feld, MS
    OPTICS LETTERS, 2001, 26 (06) : 322 - 324
  • [4] Measurement of the Pulsatile Movement of Ocular Tissues With Fourier-Domain Low-Coherence Interferometry
    Singh, K.
    Dion, C.
    Costantino, S.
    Wajszilber, M.
    Ozaki, T.
    Lesk, M.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2010, 51 (13)
  • [5] Measuring structural features using a dual window method for light scattering spectroscopy and Fourier-domain low coherence interferometry
    Robles, Francisco E.
    Wax, Adam
    BIOMEDICAL APPLICATIONS OF LIGHT SCATTERING IV, 2010, 7573
  • [6] Fourier-domain low-coherence interferometry for differential mode delay analysis of an optical fiber
    Lee, Ji Yong
    Ahn, Tae-Jung
    Moon, Sucbei
    Youk, Young Chun
    Jung, Yong Min
    Oh, Kyunghwan
    Kim, Dug Young
    OPTICS LETTERS, 2006, 31 (16) : 2396 - 2398
  • [7] Development of a clinical Fourier-domain angle resolved low-coherence interferometry system for in vivo measurements
    Terry, Neil G.
    Zhu, Yizheng
    Brown, William J.
    Wax, Adam
    BIOMEDICAL APPLICATIONS OF LIGHT SCATTERING II, 2008, 6864
  • [8] Differential mode delay analysis for a multimode optical fiber with Fourier-domain low-coherence interferometry
    Lee, J. Y.
    Ahn, T-J.
    Moon, S.
    Jung, Y.
    Oh, K.
    Kim, D. Y.
    2006 OPTICAL FIBER COMMUNICATION CONFERENCE/NATIONAL FIBER OPTIC ENGINEERS CONFERENCE, VOLS 1-6, 2006, : 554 - 556
  • [9] Spectrum-sliced Fourier-domain low-coherence interferometry for measuring the chromatic dispersion of an optical fiber
    Lee, J. Y.
    Kim, D. Y.
    APPLIED OPTICS, 2007, 46 (29) : 7289 - 7296
  • [10] Angular light scattering studies using low-coherence interferometry
    Wax, A
    Yang, CH
    Dasari, RR
    Feld, MS
    COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICAL SCIENCE AND CLINICA APPLICATIONS V, 2001, 4251 : 32 - 42
12345