In extremis diagnosis of celiac disease and concomitant wheat allergy

被引：7

作者：

Borghini, Raffaele ^{[1
]}

Donato, Giuseppe ^{[2
]}

Marino, Mariacatia ^{[1
]}

Casale, Rossela ^{[1
]}

Di Tola, Marco ^{[1
]}

Picarelli, Antonio ^{[1
]}

机构：

[1] Sapienza Univ, Dept Internal Med & Med Specialties, Rome, Italy

[2] Sapienza Univ, Dept Clin Med, Rome, Italy

来源：

TURKISH JOURNAL OF GASTROENTEROLOGY | 2018年 / 29卷 / 04期

关键词：

Celiac disease; wheat allergy; organ culture; histology; gluten-free diet; GLUTEN; PREVALENCE;

D O I：

10.5152/tjg.2018.17889

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Celiac disease (CD) and concomitant wheat allergy are not commonly described in the literature. Both can have almost the same treatment consisting of a gluten-free or wheat-free diet. On the other hand, they are based on totally different pathogenetic mechanisms and can be easily underdiagnosed, particularly CD. We describe a peculiar case of a young female patient affected by wheat allergy whose serological and histological data were not diagnostic for CD. Organ culture system successfully detected specific antibodies for CD in duodenal biopsy supernatant, supporting the diagnosis of CD.

引用

页码：515 / 517

页数：3

共 10 条

[1] Mutatis mutandis: Are we diagnosing too many people with non-celiac gluten sensitivity? Multiple case report [J].

Borghini, Raffaele ;

Donato, Giuseppe ;

Di Tola, Marco ;

Isonne, Claudia ;

Picarelli, Antonio .

TURKISH JOURNAL OF GASTROENTEROLOGY, 2014, 25 (03) :319-322

[2] Allergy prevalence in adult celiac disease [J].

Ciacci, C ;

Cavallaro, R ;

Iovino, P ;

Sabbatini, F ;

Palumbo, A ;

Amoruso, D ;

Tortora, R ;

Mazzacca, G .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 113 (06) :1199-1203

[3] Celiac disease [J].

Green, Peter H. R. ;

Lebwohl, Benjamin ;

Greywoode, Ruby .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 135 (05) :1099-1106

[4] In Vitro Gluten Challenge Test for Celiac Disease Diagnosis [J].

Khalesi, Maryam ;

Jafari, Seyed Ali ;

Kiani, Mohammadali ;

Picarelli, Antonio ;

Borghini, Raffaele ;

Sadeghi, Ramin ;

Eghtedar, Alireza ;

Ayatollahi, Hosein ;

Kianifar, Hamid R. .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2016, 62 (02) :276-283

[5] Suspected Nonceliac Gluten Sensitivity Confirmed in Few Patients After Gluten Challenge in Double-Blind, Placebo-Controlled Trials [J].

Molina-Infante, Javier ;

Carroccio, Antonio .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2017, 15 (03) :339-348

[6] Prevalence of Wheat Allergy in Japanese Adults [J].

Morita, Eishin ;

Chinuki, Yuko ;

Takahashi, Hitoshi ;

Nabika, Tohru ;

Yamasaki, Masayuki ;

Shiwaku, Kuninori .

ALLERGOLOGY INTERNATIONAL, 2012, 61 (01) :101-105

[7] Weaknesses of histological analysis in celiac disease diagnosis: new possible scenarios [J].

Picarelli, Antonio ;

Borghini, Raffaele ;

Donato, Giuseppe ;

Di Tola, Marco ;

Boccabella, Cristina ;

Isonne, Claudia ;

Giordano, Marco ;

Di Cristofano, Claudio ;

Romeo, Francesco ;

Di Cioccio, Giuseppe ;

Marcheggiano, Adriana ;

Villanacci, Vincenzo ;

Tiberti, Antonio .

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2014, 49 (11) :1318-1324

[8] Reactivity to dietary gluten: new insights into differential diagnosis among gluten-related gastrointestinal disorders [J].

Picarelli, Antonio ;

Borghini, Raffaele ;

Isonne, Claudia ;

Di Tola, Marco .

POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ-POLISH ARCHIVES OF INTERNAL MEDICINE, 2013, 123 (12) :708-712

[9]

Torres JA, 2008, J INVEST ALLERG CLIN, V18, P412

[10] IgE-Mediated allergy to wheat in a child with celiac disease - a case report [J].

Wong, Tiffany ;

Ko, Hin Hin ;

Chan, Edmond S. .

ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, 2014, 10

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