Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

被引：267

作者：

Cobine, Paul A. ^{[1
]}

Brady, Donita C. ^{[2
,3
]}

机构：

[1] Auburn Univ, Dept Biol Sci, Auburn, AL 36849 USA

[2] Univ Penn, Dept Canc Biol, Perelman Sch Med, Philadelphia, PA 19104 USA

[3] Univ Penn, Abramson Family Canc Res Inst, Perelman Sch Med, Philadelphia, PA 19104 USA

来源：

MOLECULAR CELL | 2022年 / 82卷 / 10期

关键词：

CU;

D O I：

10.1016/j.molcel.2022.05.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tsvetkov et al. (2022) discovered a new form of cell death triggered by targeted accumulation of Cu in mito-chondria that drives lipoylated TCA cycle enzyme aggregation via direct Cu binding.

引用

页码：1786 / 1787

页数：2

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