Concise Total Synthesis of (±)-Lycodine

被引：39

作者：

Tsukano, Chihiro ^{[1
]}

Zhao, Le ^{[2
]}

Takemoto, Yoshiji ^{[1
]}

Hirama, Masahiro ^{[2
]}

机构：

[1] Kyoto Univ, Dept Organ Chem, Grad Sch Pharmaceut Sci, Sakyo Ku, Kyoto, Japan

[2] Tohoku Univ, Dept Chem, Grad Sch Sci, Aoba Ku, Sendai, Miyagi 980, Japan

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 2010卷 / 22期

基金：

日本学术振兴会;

关键词：

Alkaloids; Total synthesis; Heck reaction; Cycloaddition; HUPERZINE-A; HECK REACTION; LYCOPODIUM; ALKALOIDS; (+)-COMPLANADINE; ANNULATION; ANALOGS; AGENT;

D O I：

10.1002/ejoc.201000667

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lycodine is a representative Lycopodium alkaloid, which features a bicyclo[3 3 1]nonane core and pyridine and piperidine rings. Stereoselective total synthesis of lycodine was achieved using Diels-Alder and intramolecular Mizoroki-Heck reactions

引用

页码：4198 / 4200

页数：3

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