Vaccine immune pressure influences viral population complexity of avian influenza virus during infection

被引：9

作者：

Milani, Adelaide ^{[1
]}

Fusaro, Alice ^{[1
]}

Bonfante, Francesco ^{[1
]}

Zamperin, Gianpiero ^{[1
]}

Salviato, Annalisa ^{[1
]}

Mancin, Marzia ^{[1
]}

Mastrorilli, Eleonora ^{[1
]}

Hughes, Joseph ^{[5
]}

Hussein, Hussein A. ^{[2
]}

Hassan, Magdi ^{[3
]}

Mundt, Egbert ^{[6
]}

Terregino, Calogero ^{[1
]}

Cattoli, Giovanni ^{[1
,4
]}

Monne, Isabella ^{[1
]}

机构：

[1] Ist Zooprofilatt Sperimentale Venezie, Padua, Italy

[2] Cairo Univ, Virol Dept, Fac Vet Med, Giza, Egypt

[3] IFT Corp, Cairo, Egypt

[4] IAEA, Joint FAO IAEA Div, Anim Prod & Hlth Lab, Seibersdorf, Austria

[5] Univ Glasgow, MRC, Ctr Virus Res, Glasgow, Lanark, Scotland

[6] Boehringer Ingelheim Vet Res Ctr, D-30559 Hannover, Germany

来源：

VETERINARY MICROBIOLOGY | 2017年 / 203卷

关键词：

Influenza A virus; H5N1; Vaccine; Deep sequencing; Evolution; HEMAGGLUTININ MOLECULE; EVOLUTIONARY DYNAMICS; ANTIGENIC DRIFT; A VIRUS; H5; FRAMEWORK; SITES;

D O I：

10.1016/j.vetmic.2017.02.016

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Vaccines are useful tools to control influenza A virus infection in poultry, but they need to be periodically reformulated to guarantee appropriate protection from infection and to limit viral replication and circulation, which could favour the emergence of new variants. In this study, a deep sequencing approach was used to characterize and follow the evolution of the hemagglutinin of the H5N1 highly pathogenic avian influenza viral population in infected animals vaccinated with two vaccines conferring different protection levels. Results from this preliminary investigation suggested that the evolution of the viral population, as well as the abundance and heterogeneity of minority variants could be influenced by the immune pressure conferred by vaccination. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：88 / 94

页数：7

共 26 条

[1] Phylodynamics of avian influenza clade 2.2.1 H5N1 viruses in Egypt [J].

Arafa, Abdelsatar ;

El-Masry, Ihab ;

Kholosy, Shereen ;

Hassan, Mohammed K. ;

Dauphin, Gwenaelle ;

Lubroth, Juan ;

Makonnen, Yilma J. .

VIROLOGY JOURNAL, 2016, 13

[2] Trimmomatic: a flexible trimmer for Illumina sequence data [J].

Bolger, Anthony M. ;

Lohse, Marc ;

Usadel, Bjoern .

BIOINFORMATICS, 2014, 30 (15) :2114-2120

[3] Evidence for differing evolutionary dynamics of A/H5N1 viruses among countries applying or not applying avian influenza vaccination in poultry [J].

Cattoli, Giovanni ;

Fusaro, Alice ;

Monne, Isabella ;

Coven, Fethiye ;

Joannis, Tony ;

El-Hamid, Hatem S. Abd ;

Hussein, Aly Ahmed ;

Cornelius, Claire ;

Amarin, Nadim Mukhles ;

Mancin, Marzia ;

Holmes, Edward C. ;

Capua, Ilaria .

VACCINE, 2011, 29 (50) :9368-9375

[4] Antigenic Drift in H5N1 Avian Influenza Virus in Poultry Is Driven by Mutations in Major Antigenic Sites of the Hemagglutinin Molecule Analogous to Those for Human Influenza Virus [J].

Cattoli, Giovanni ;

Milani, Adelaide ;

Temperton, Nigel ;

Zecchin, Bianca ;

Buratin, Alessandra ;

Molesti, Eleonora ;

Aly, Mona Meherez ;

Arafa, Abdel ;

Capua, Ilaria .

JOURNAL OF VIROLOGY, 2011, 85 (17) :8718-8724

[5] A genetically engineered H5 protein expressed in insect cells confers protection against different clades of H5N1 highly pathogenic avian influenza viruses in chickens [J].

Cavalcanti, Marcia Oliveira ;

Vaughn, Eric ;

Capua, Ilaria ;

Cattoli, Giovanni ;

Terregino, Calogero ;

Harder, Timm ;

Grund, Christian ;

Vega, Carlos ;

Robles, Francisco ;

Franco, Julio ;

Darji, Ayub ;

Arafa, Abdel-Satar ;

Mundt, Egbert .

AVIAN PATHOLOGY, 2017, 46 (02) :224-233

[6] A framework for variation discovery and genotyping using next-generation DNA sequencing data [J].

DePristo, Mark A. ;

Banks, Eric ;

Poplin, Ryan ;

Garimella, Kiran V. ;

Maguire, Jared R. ;

Hartl, Christopher ;

Philippakis, Anthony A. ;

del Angel, Guillermo ;

Rivas, Manuel A. ;

Hanna, Matt ;

McKenna, Aaron ;

Fennell, Tim J. ;

Kernytsky, Andrew M. ;

Sivachenko, Andrey Y. ;

Cibulskis, Kristian ;

Gabriel, Stacey B. ;

Altshuler, David ;

Daly, Mark J. .

NATURE GENETICS, 2011, 43 (05) :491-+

[7] Genome plasticity of triple-reassortant H1N1 influenza A virus during infection of vaccinated pigs [J].

Diaz, Andres ;

Enomoto, Shinichiro ;

Romagosa, Anna ;

Sreevatsan, Srinand ;

Nelson, Martha ;

Culhane, Marie ;

Torremorell, Montserrat .

JOURNAL OF GENERAL VIROLOGY, 2015, 96 :2982-2993

[8] Antigenic drift of H1N1 influenza A virus in pigs with and without passive immunity [J].

Diaz, Andres ;

Allerson, Matthew ;

Culhane, Marie ;

Sreevatsan, Srinand ;

Torremorell, Montserrat .

INFLUENZA AND OTHER RESPIRATORY VIRUSES, 2013, 7 :52-60

[9] Intrahost Evolutionary Dynamics of Canine Influenza Virus in Naive and Partially Immune Dogs [J].

Hoelzer, Karin ;

Murcia, Pablo R. ;

Baillie, Gregory J. ;

Wood, James L. N. ;

Metzger, Stephan M. ;

Osterrieder, Nikolaus ;

Dubovi, Edward J. ;

Holmes, Edward C. ;

Parrish, Colin R. .

JOURNAL OF VIROLOGY, 2010, 84 (10) :5329-5335

[10] Epitope mapping of the hemagglutinin molecule of a highly pathogenic H5N1 influenza virus by using [J].

Kaverin, Nikolai V. ;

Rudneva, Irina A. ;

Govorkova, Elena A. ;

Timofeeva, Tatyana A. ;

Shilov, Aleksandr A. ;

Kochergin-Nikitsky, Konstantin S. ;

Krylov, Piotr S. ;

Webster, Robert G. .

JOURNAL OF VIROLOGY, 2007, 81 (23) :12911-12917

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