The Differential Diagnosis of Acute Onset Truncal Ataxia: The Importance of Dysgeusia in Miller Fisher Syndrome

被引:2
作者
Ueno, Tatsuya [1 ]
Kimura, Ryoya [1 ]
Kon, Tomoya [1 ]
Haga, Rie [1 ]
Nishijima, Haruo [1 ]
Nunomura, Jin-ichi [1 ]
Tomiyama, Masahiko [1 ]
机构
[1] Aomori Prefectural Cent Hosp, Dept Neurol, Aomori, Japan
关键词
dysgeusia; taste impairment; ataxia; Miller Fisher syndrome; GQ1b; differential diagnosis; GUILLAIN-BARRE-SYNDROME; TASTE IMPAIRMENT; ANTIBODY SYNDROME; CLASSIFICATION; NEUROPATHY; INFARCTION;
D O I
10.2169/internalmedicine.0313-17
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Miller Fisher syndrome (MFS) can be difficult to diagnose, particularly in mild eases where some of the standard triad of symptoms (external ophthalmoplegia, ataxia, and loss of deep tendon reflex) are absent. We herein report a case of the incomplete form of MFS diagnosed in a 54-year-old Japanese man who presented only with ataxia symptoms and was positive for the anti-GQ1b antibody. However, the patient also suffered from dysgeusia, a significant impairment of taste perception. We propose that dysgeusia in acute-onset ataxia cases may constitute an important clinical feature to aid in the diagnosis of the incomplete form of MFS.
引用
收藏
页码:2057 / 2060
页数:4
相关论文
共 21 条
[1]  
Berkowitz Aaron L, 2014, Pract Neurol, V14, P14, DOI 10.1136/practneurol-2013-000651
[2]   The Diagnostic Accuracy of Truncal Ataxia and HINTS as Cardinal Signs for Acute Vestibular Syndrome [J].
Carmona, Sergio ;
Martinez, Carlos ;
Zalazar, Guillermo ;
Moro, Marcela ;
Batuecas-Caletrio, Angel ;
Luis, Leonel ;
Gordon, Carlos .
FRONTIERS IN NEUROLOGY, 2016, 7
[3]  
Daroff R.B., 2015, Bradley's Neurology in Clinical Practice
[4]   A case of recurrent Miller Fisher syndrome mimicking botulism [J].
Doerr, J. ;
Dieste, F. J. ;
van Husen, D. Klaasen ;
Zipp, F. ;
Vogel, H. P. .
NEUROLOGICAL SCIENCES, 2006, 27 (06) :424-425
[6]   Sporadic ataxia with adult onset: classification and diagnostic criteria [J].
Klockgether, Thomas .
LANCET NEUROLOGY, 2010, 9 (01) :94-104
[7]   The wide spectrum of clinical manifestations in Sjogren's syndrome-associated neuropathy [J].
Mori, K ;
Iijima, M ;
Koike, H ;
Hattori, N ;
Tanaka, F ;
Watanabe, H ;
Katsuno, M ;
Fujita, A ;
Aiba, I ;
Ogata, A ;
Saito, T ;
Asakura, K ;
Yoshida, M ;
Hirayama, M ;
Sobue, G .
BRAIN, 2005, 128 :2518-2534
[8]   Taste impairment in Guillain-Barre syndrome: more frequent than thought? [J].
Nishijima, Haruo ;
Tomiyama, Masahiko ;
Suzuki, Chieko ;
Kon, Tomoya ;
Funamizu, Yukihisa ;
Ueno, Tatsuya ;
Haga, Rie ;
Miki, Yasuo ;
Arai, Akira ;
Baba, Masayuki ;
Kimura, Tamaki .
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2011, 16 (03) :270-271
[9]   Guillain-Barre syndrome presenting with loss of taste [J].
Odaka, M ;
Yuki, N ;
Nishimoto, Y ;
Hirata, K .
NEUROLOGY, 2002, 58 (09) :1437-1438
[10]   Anti-GQ1b IgG antibody syndrome: clinical and immunological range [J].
Odaka, M ;
Yuki, N ;
Hirata, K .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2001, 70 (01) :50-55