The identification of synergism in the sufficient-component-cause framework

被引：140

作者：

VanderWeele, Tyler J.

Robins, James M.

机构：

[1] Univ Chicago, Dept Hlth Studies, Chicago, IL 60637 USA

[2] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

[3] Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA

来源：

EPIDEMIOLOGY | 2007年 / 18卷 / 03期

关键词：

D O I：

10.1097/01.ede.0000260218.66432.88

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Various concepts of interaction are reconsidered in light of a sufficient-component-cause framework. Conditions and statistical tests are derived for the presence of synergism within sufficient causes. The conditions derived are sufficient but not necessary for the presence of synergism. In the context of monotonic effects, the conditions derived are closely related to effect modification on the risk difference scale; however, this is not the case without the assumption of monotonic effects.

引用

页码：329 / 339

页数：11

共 25 条

[1] SYNERGISM AND INTERACTION - ARE THEY EQUIVALENT [J].