Anomalous phosphenes in ocular protontherapy

被引:14
作者
Khan, E. [1 ]
Marechal, F. [1 ]
Dendale, R. [2 ]
Mabit, C. [2 ]
Calugaru, V. [2 ]
Desjardin, L. [2 ]
Narici, L. [3 ]
机构
[1] Univ Paris 11, Inst Phys Nucl, IN2P3, CNRS, F-91406 Orsay, France
[2] Ctr Protontherapie Orsay, Inst Curie, F-91898 Orsay, France
[3] Univ Roma Tor Vergata, Dept Phys, I-00133 Rome, Italy
关键词
Protons; Phosphenes; Light flashes; ALTEA; LIGHT-FLASHES; SPACE; RADIATION; TRAVEL;
D O I
10.1016/j.asr.2009.11.021
中图分类号
V [航空、航天];
学科分类号
08 ; 0825 ;
摘要
We have undertaken a clinical ground study of proton-induced light flashes (phosphenes). Patients treated at the Instiiut Curie - Centre de Protontherapie in Orsay, France, received radiation therapy to cure ocular and skull-base cancers. Sixty percent of the patients treated for choroidal melanomas using 73 MeV protons report anomalous phosphenes. Delivering a radiation dose on the retina only is not sufficient to trigger the light flash. The present study may be the first indication of phosphenes triggered by protons of few tens of MeV. (C) 2009 COSPAR. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:846 / 849
页数:4
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