The Wnt signaling pathway and bone metabolism

被引：132
|
作者：
Johnson, Mark L.
Kamel, Mohamed A.
机构：
[1] Univ Missouri, Sch Dent, Dept Oral Biol, Kansas City, MO 64108 USA
[2] Suez Canal Univ, Sch Med, Dept Rheumatol & Rehabil, Ismailia, Egypt
来源：
CURRENT OPINION IN RHEUMATOLOGY | 2007年 / 19卷 / 04期
关键词：
beta-catenin; arthritis; low-density lipoprotein receptor related protein 5; sclerostin; Wnt;
D O I：
10.1097/BOR.0b013e32816e06f9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Understanding the role that the Writ signaling pathways play in the regulation of bone metabolism offers great promise for the developmental of new paradigms and pharmaceutical strategies for the treatment of various 1 diseases such as osteoporosis, rheumatoid arthritis and osteoarthritis. Progress in this regard has already been made.
引用
收藏
页码：376 / 382
页数：7
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