Oral antibiotic prescribing by NHS dentists in England 2010-2017

被引:41
作者
Thornhill, Martin H. [1 ,2 ]
Dayer, Mark J. [3 ]
Durkin, Michael J. [4 ]
Lockhart, Peter B. [2 ]
Baddour, Larry M. [5 ,6 ]
机构
[1] Univ Sheffield, Sch Clin Dent, Unit Oral & Maxillofacial Med Surg & Pathol, Sheffield, S Yorkshire, England
[2] Carolinas Med Ctr, Dept Oral Med, Charlotte, NC 28203 USA
[3] Taunton & Somerset NHS Trust, Dept Cardiol, Taunton, Somerset, England
[4] Washington Univ, Sch Med, Div Infect Dis, St Louis, MO 63110 USA
[5] Mayo Clin, Dept Med, Div Infect Dis, Coll Med, Rochester, MN USA
[6] Mayo Clin, Dept Cardiovasc Med, Coll Med, Rochester, MN USA
关键词
ANTIMICROBIAL SUSCEPTIBILITY; DENTAL PRACTITIONERS; ADVERSE-REACTIONS; BACTERIA; PRESCRIPTIONS; METRONIDAZOLE; CLINDAMYCIN; PREVENTION; INFECTION; ABSCESSES;
D O I
10.1038/s41415-019-1002-3
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Introduction Dentists prescribe a significant proportion of all antibiotics, while antimicrobial stewardship aims to minimise antibiotic-prescribing to reduce the risk of developing antibiotic-resistance and adverse drug reactions. Aims To evaluate NHS antibiotic-prescribing practices of dentists in England between 2010-2017. Methods NHS Digital 2010-2017 data for England were analysed to quantify dental and general primary-care oral antibiotic prescribing. Results Dental prescribing accounted for 10.8% of all oral antibiotic prescribing, 18.4% of amoxicillin and 57.0% of metronidazole prescribing in primary care. Amoxicillin accounted for 64.8% of all oral antibiotic prescribing by dentists, followed by metronidazole (28.0%), erythromycin (4.4%), phenoxymethylpenicillin (0.9%), clindamycin (0.6%), co-amoxiclav (0.5%), cephalosporins (0.4%) and tetracyclines (0.3%). Prescriptions by dentists declined during the study period for all antibiotics except for co-amoxiclav. This increase is of concern given the need to restrict co-amoxiclav use to infections where there is no alternative. Dental prescribing of clindamycin, which accounted for 43.9% of primary care prescribing in 2010, accounted for only 14.6% in 2017. Overall oral antibiotic prescribing by dentists fell 24.4% as compared to 14.8% in all of primary care. Conclusions These data suggest dentists have reduced antibiotic prescribing, possibly more than in other areas of primary-care. Nonetheless, opportunities remain for further reduction.
引用
收藏
页码:1044 / 1050
页数:7
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