Drug therapy during pregnancy: implications for dental practice

被引：15

作者：

Ouanounou, A. ^{[1
]}

Haas, D. A. ^{[2
]}

机构：

[1] Univ Toronto, Fac Dent, Dept Clin Sci, Toronto, ON M5S 1A1, Canada

[2] Univ Toronto, Fac Med, Dept Pharmacol, Fac Dent, Toronto, ON M5S 1A1, Canada

来源：

BRITISH DENTAL JOURNAL | 2016年 / 220卷 / 08期

关键词：

NONSTEROIDAL ANTIINFLAMMATORY DRUGS; MAJOR MALFORMATIONS; PRETERM DELIVERY; METRONIDAZOLE; EXPOSURE; SAFETY; RISK; PHARMACOKINETICS; BENZODIAZEPINES; ACETAMINOPHEN;

D O I：

10.1038/sj.bdj.2016.299

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Pregnancy is accompanied by various physiological and physical changes, including those found in the cardiovascular, respiratory, gastrointestinal, renal and haematological systems. These alterations in the pregnant patient may potentially affect drug pharmacokinetics. Also, pharmacotherapy presents a unique matter due to the potential teratogenic effects of certain drugs. Although medications prescribed by dentists are generally safe during pregnancy, some modifications may be needed. In this article we will discuss the changes in the physiology during pregnancy and its impact on drug therapy. Specific emphasis will be given to the drugs commonly given by dentists, namely, local anaesthetics, analgesics, antibiotics and sedatives.

引用

页码：413 / 417

页数：5

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