Myorelaxant and antispasmodic effects of the essential oil of Alpinia speciosa on rat ileum

被引：2
|
作者：
Bezerra, MAC
Leal-Cardoso, JH
Coelho-de-Souza, AN
Criddle, DN
Fonteles, MC
机构：
[1] Univ Estadual Ceara, Ctr Ciencias Saude, BR-60740000 Fortaleza, Ceara, Brazil
[2] Univ Vale Acarau, Ctr Ciencias Saude, BR-62040370 Sobral, CE, Brazil
[3] Univ Estadual Ceara, Fac Vet, BR-60740000 Fortaleza, Ceara, Brazil
来源：
PHYTOTHERAPY RESEARCH | 2000年 / 14卷 / 07期
关键词：
essential oil; Alpinia speciosa; ileum; antispasmodic;
D O I：
10.1002/1099-1573(200011)14:7<549::AID-PTR623>3.0.CO;2-T
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The effects of the essential oil of Alpinia speciosa Schum (EOAS) on rat ileum were studied. EOAS (0.1-600 mug/mL) reversibly relaxed ileal basal tonus, Submaximal contractions induced by 60 mM KCI or acetylcholine were concentration dependently inhibited by EOAS with similar IC50 values (similar to 44 and 48 mug/mL, respectively). These results show that EOAS possesses both relaxant and antispasmodic actions in the ileum, Copyright (C) 2000 John Wiley & Sons, Ltd.
引用
收藏
页码：549 / 551
页数：3
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