Highly Regioselective Synthesis of Novel 1,4′-Bipyrazoles

被引：5

作者：

Martins, Marcos A. P. ^{[1
]}

Fiss, Gabriela F. ^{[1
]}

Frizzo, Clarissa P. ^{[1
]}

Rosa, Fernanda A. ^{[1
]}

Bonacorso, Helio G. ^{[1
]}

Zanatta, Nilo ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Quim, Nucleo Quim Heterociclos, BR-97105900 Santa Maria, RS, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2010年 / 21卷 / 02期

关键词：

enaminones; bipyrazoles; heterocycles; cyclocondensation; regioselectivity; SOLID-STATE NMR; X-RAY; MOLECULAR-STRUCTURE; PYRAZOLES; DERIVATIVES; SUBSTITUENT; DYNAMICS; PROTON;

D O I：

10.1590/S0103-50532010000200008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel 1,4'-bipyrazoles were synthesized via highly regioselective cyclocondensation reactions of b-dimethylaminoenones with hydrazine monohydrate, tert-butylhydrazine hydrochloride, phenylhydrazine hydrochloride or carboxymethylhydrazine. X-ray diffraction technique was used in the elucidation of the regiochemistry of the beta-dimethylaminoenaminones and of the 1,4'-bipyrazoles. 1,4'-Bipyrazolylisoxazoles were also reported.

引用

页码：240 / 247

页数：8

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