Enhanced Resolution of Low Molecular Weight Poly(Ethylene Glycol) in Nanopore Analysis

被引：22

作者：

Cao, Chan

Ying, Yi-Lun

Gu, Zhen

Long, Yi-Tao ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China

来源：

ANALYTICAL CHEMISTRY | 2014年 / 86卷 / 24期

关键词：

ALPHA-HEMOLYSIN NANOPORE; MASS-SPECTROMETRY; POLYETHYLENE-GLYCOL; NUCLEIC-ACIDS; PROTEIN PORE; DNA; TRANSPORT; PEPTIDES; POLYMERS; DYNAMICS;

D O I：

10.1021/ac504233s

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A design with conjugation of DNA hairpin structure to the poly(ethylene glycol) molecule was presented to enhance the temporal resolution of low molecular weight poly(ethylene glycol) in nanopore studies. By the virtue of this design, detection of an individual PEG with molecular weight as low as 140 Da was achieved at the single-molecule level in solution, which provides a novel strategy for characterization of an individual small molecule within a nanopore. Furthermore, we found that the current duration time of poly(ethylene glycol) was scaled with the relative molecular weight, which has a potential application in single-molecule detection.

引用

页码：11946 / 11950

页数：5

共 50 条

[31] Enhanced crystallization behaviors of poly(ethylene terephthalate) via adding expanded graphite and poly(ethylene glycol)
Su, Juan-juan
Yang, Guang-hui
Zhou, Tian-nan
Gao, Xiang
Wang, Ke
Fu, Qiang
COLLOID AND POLYMER SCIENCE, 2013, 291 (04) : 911 - 917
[32] Liposomes with Low Levels of Grafted Poly(ethylene glycol) Remain Susceptible to Destabilization by Anti-Poly(ethylene glycol) Antibodies
Chen, Bing-Mae
Chen, Even
Lin, Yi-Chen
Tran, Trieu Thi My
Turjeman, Keren
Yang, Shih-Hung
Cheng, Tian-Lu
Barenholz, Yechezkel
Roffler, Steve R.
ACS NANO, 2024, 18 (33) : 22122 - 22138
[33] Production and characterization of poly(3-hydroxybutyrateco-3-hydroxyhexanoate)-poly(ethylene glycol) hybird copolymer with adjustable molecular weight
Zhang, Ya-li
Lu, Xiao-yun
Liu, Qian-qian
Li, Ming-chuan
Yang, Zhi-qian
Ma, Jian-gang
CHINESE JOURNAL OF POLYMER SCIENCE, 2012, 30 (01) : 101 - 111
[34] Production and characterization of poly(3-hydroxybutyrateco-3-hydroxyhexanoate)-poly(ethylene glycol) hybird copolymer with adjustable molecular weight
Ya-li Zhang
Xiao-yun Lu
Qian-qian Liu
Ming-chuan Li
Zhi-qian Yang
Jian-gang Ma
Chinese Journal of Polymer Science, 2012, 30 : 101 - 111
[35] Prevention of inter fi bril horni fi cation by replacing water in nanocellulose gel with low molecular weight liquid poly(ethylene glycol)
Santmarti, Alba
Tammelin, Tekla
Lee, Koon-Yang
CARBOHYDRATE POLYMERS, 2020, 250
[36] Determination of the molecular weight of poly(ethylene glycol) in biological samples by reversed-phase LC-MS with in-source fragmentation
Warrack, Bethanne M.
Redding, Brian P.
Chen, Guodong
Bolgar, Mark S.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2013, 405 (12) : 4283 - 4287
[37] Spontaneous growth of gold nanoclusters to form gold nanoparticles in the presence of high molecular weight poly(ethylene glycol)
Uehara, Nobuo
Sonoda, Natsumi
Iwamatsu, Tsubasa
Haneishi, Chikara
Inagawa, Arinori
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2020, 585
[38] The effect of different molecular weight of poly(ethylene glycol) on the electrokinetic and rheological properties of Na-bentonite suspensions
Tunc, Sibel
Duman, Osman
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2008, 317 (1-3) : 93 - 99
[39] Influence of poly(ethylene glycol)-containing additives on the sliding wear of ultrahigh molecular weight polyethylene/polypropylene blend
Xie, Meiju
Chen, Jinyao
Li, Huilin
Li, Meng
WEAR, 2010, 268 (5-6) : 730 - 736
[40] Viscosity reduction and disentanglement in ultrahigh molecular weight polyethylene melt: Effect of blending with polypropylene and poly(ethylene glycol)
Xie, Meiju
Li, Huilin
EUROPEAN POLYMER JOURNAL, 2007, 43 (08) : 3480 - 3487

← 1 2 3 4 5 →