Effect of HIV infection on the outcome of cancer therapy in children

被引：4

作者：

Stefan, Daniela C. ^{[1
,2
]}

机构：

[1] Tygerberg Hosp, Dept Paediat & Child Hlth, Cape Town, South Africa

[2] Univ Stellenbosch, Cape Town, South Africa

来源：

LANCET ONCOLOGY | 2014年 / 15卷 / 12期

关键词：

HUMAN-IMMUNODEFICIENCY-VIRUS; EPSTEIN-BARR-VIRUS; STEM-CELL TRANSPLANTATION; NON-HODGKINS-LYMPHOMA; KAPOSIS-SARCOMA; BURKITT-LYMPHOMA; AIDS; EPIDEMIC; MALIGNANCIES; IDENTIFICATION;

D O I：

10.1016/S1470-2045(14)70313-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Systematic studies comparing the outcomes of cancer treatment between children with and without HIV are scarce. The literature seems to suggest that, even with present therapeutic advances, prognosis is poor with HIV infection. The aim of this Review was to assess scientific publications from 1990 to present, addressing the difficulties associated with treatment of cancer in children with AIDS and the adaptive changes in therapy. Although much progress has been achieved, further research is needed about antiretroviral and cytotoxic drug interactions, the optimum use of supportive therapy including stem cells and bone marrow transplant, the timing of the initiation of highly active antiretroviral therapy, and the optimum use of protease inhibitors.

引用

页码：E562 / E567

页数：6

共 52 条

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