Impact of grape pomace flour (GPF) on immunity and immune-antioxidant-anti-inflammatory genes expression in Labeo rohita against Flavobacterium columnaris

被引:32
作者
Harikrishnan, Ramasamy [1 ]
Devi, Gunapathy [2 ]
Hien Van Doan [3 ,4 ]
Balasundaram, Chellam [5 ]
Esteban, Maria Angeles [6 ]
Abdel-Tawwab, Mohsen [7 ]
机构
[1] Pachaiyappas Coll Men, Dept Zool, Kanchipuram 631501, Tamil Nadu, India
[2] Nehru Mem Coll, Dept Zool, Puthanampatti 621007, Tamil Nadu, India
[3] Chiang Mai Univ, Fac Agr, Dept Anim & Aquat Sci, Chiang Mai 50200, Thailand
[4] Chiang Mai Univ, Sci & Technol Res Inst, 239 Huay Keaw Rd, Chiang Mai 50200, Thailand
[5] Tamil Univ, Dept Herbal & Environm Sci, Thanjavur 613005, Tamil Nadu, India
[6] Univ Murcia, Fac Biol, Dept Cell Biol & Histol, Fish Innate Immune Syst Grp, Reg Campus Int Excellence Campus Mare Nostrum, Murcia 30100, Spain
[7] Cent Lab Aquaculture Res, Dept Fish Biol & Ecol, Abo Hammad, Sharqia, Egypt
关键词
Antioxidant; Flavobacterium columnaris; Grape pomace flour (GPF); Innate-adaptive immune response; Labeo rohita; VITIS-VINIFERA L; SEED PROANTHOCYANIDIN EXTRACT; TOTAL PHENOLIC CONTENTS; GROWTH-PERFORMANCE; OXIDATIVE STRESS; FREE-RADICALS; INNATE IMMUNITY; FUNCTIONAL COMPONENTS; STAPHYLOCOCCUS-AUREUS; CHEMICAL-COMPOSITION;
D O I
10.1016/j.fsi.2021.01.011
中图分类号
S9 [水产、渔业];
学科分类号
0908 ;
摘要
This study evaluates the effects of dietary inclusion of grape pomace flour (GPF) on growth, antioxidant, antiinflammatory, innate-adaptive immunity, and immune genes expression in Labeo rohita against Flavobacterium columnaris. In both normal and challenged fish the growth rate, hematology and biochemical parameters significantly increased when fed with 200 and 300 mg GPF enriched diets; similarly the activities of antioxidants and innate-adaptive immune parameters, such as malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione (GSH), phagocytic (PC), respiratory burst (RB), alternative pathway complement (ACP), lysozyme (Lyz), and total immunoglobulin M (IgM) significantly increased in both groups. Similarly, the immune, antioxidant, and anti-inflammatory-related gene mRNA expression was significantly up regulated in head kidney (HK) tissues. The challenged fish fed without GPF always exhibited lower values of all the studied parameters. The results indicate that both normal and challenged fish treated with 200 mg GPF inclusion diet had significantly enhanced growth rate, antioxidant status, and immune defense mechanisms than with 300 mg GPF diet in L. rohita against F. columnaris.
引用
收藏
页码:69 / 82
页数:14
相关论文
共 113 条
  • [91] Antioxidant and Hepatoprotective Effects of Methanolic Extracts of Zilla spinosa and Hammada elegans Against Carbon Tetrachloride-induced Hepatotoxicity in Rats
    Ullah, Riaz
    Alsaid, Mansour S.
    Shahat, Abdelaaty A.
    Naser, Almoqbil Abdulaziz
    Al-Mishari, Abdullah A.
    Adnan, Muhammad
    Tariq, Akash
    [J]. OPEN CHEMISTRY, 2018, 16 (01): : 133 - 140
  • [92] Urquiaga I, 2015, BIOL RES, V48, DOI [10.1186/s40659-015-0040-9, 10.1186/S40659-015-0040-9]
  • [93] Van Houten Bennett, 2018, Current Opinion in Toxicology, V7, P9, DOI 10.1016/j.cotox.2017.10.009
  • [94] Antibacterial and antioxidant properties of grape stem extract applied as disinfectant in fresh leafy vegetables
    Vazquez-Armenta, F. J.
    Silva-Espinoza, B. A.
    Cruz-Valenzuela, M. R.
    Gonzalez-Aguilar, G. A.
    Nazzaro, F.
    Fratianni, F.
    Ayala-Zavala, J. F.
    [J]. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2017, 54 (10): : 3192 - 3200
  • [95] Vivancos M., 2008, BRIT J NUTR, V99, P1199
  • [96] Effects of dietary polyphenol-rich grape products on intestinal microflora and gut morphology in broiler chicks
    Viveros, A.
    Chamorro, S.
    Pizarro, M.
    Arija, I.
    Centeno, C.
    Brenes, A.
    [J]. POULTRY SCIENCE, 2011, 90 (03) : 566 - 578
  • [97] Effect of dietary antioxidant supplementation on the oxidative status of plasma in broilers
    Vossen, E.
    Ntawubizi, M.
    Raes, K.
    Smet, K.
    Huyghebaert, G.
    Arnouts, S.
    De Smet, S.
    [J]. JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2011, 95 (02) : 198 - 205
  • [98] Influence of Grape Seed Proanthocyanidin Extract in Broiler Chickens: Effect on Chicken Coccidiosis and Antioxidant Status
    Wang, M. L.
    Suo, X.
    Gu, J. H.
    Zhang, W. W.
    Fang, Q.
    Wang, X.
    [J]. POULTRY SCIENCE, 2008, 87 (11) : 2273 - 2280
  • [99] Webster D., 1977, Clinical Chemistry, V23, P663
  • [100] Dietary tryptophan modulates intestinal immune response, barrier function, antioxidant status and gene expression of TOR and Nrf2 in young grass carp (Ctenopharyngodon idella)
    Wen, Hailang
    Feng, Lin
    Jiang, Weidan
    Liu, Yang
    Jiang, Jun
    Li, Shuhong
    Tang, Ling
    Zhang, Yongan
    Kuang, Shengyao
    Zhou, Xiaoqiu
    [J]. FISH & SHELLFISH IMMUNOLOGY, 2014, 40 (01) : 275 - 287