Overcoming delivery barriers with LNPs

被引：20
作者：
Jadhav, Satish G. [1 ]
Dowdy, Steven F. [1 ]
机构：
[1] Univ Calif San Diego, Sch Med, Dept Cellular & Mol Med, La Jolla, CA 92093 USA
来源：
NATURE MATERIALS | 2021年 / 20卷 / 05期
关键词：
LIPID NANOPARTICLES;
D O I：
10.1038/s41563-021-00988-3
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Ionizable phospholipids have been developed to enhance the delivery of mRNA and sgRNA for gene editing by selective organ targeting and endosomal membrane destabilization.
引用
收藏
页码：575 / 577
页数：3
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