Overcoming delivery barriers with LNPs

被引：21

作者：

Jadhav, Satish G. ^{[1
]}

Dowdy, Steven F. ^{[1
]}

机构：

[1] Univ Calif San Diego, Sch Med, Dept Cellular & Mol Med, La Jolla, CA 92093 USA

来源：

NATURE MATERIALS | 2021年 / 20卷 / 05期

关键词：

LIPID NANOPARTICLES;

D O I：

10.1038/s41563-021-00988-3

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Ionizable phospholipids have been developed to enhance the delivery of mRNA and sgRNA for gene editing by selective organ targeting and endosomal membrane destabilization.

引用

页码：575 / 577

页数：3

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