Thyroid and leptin

被引：88

作者：

Feldt-Rasmussen, Ulla ^{[1
]}

机构：

[1] Natl Univ Hosp, Rigshosp, Dept Med Endocrinol, DK-2100 Copenhagen, Denmark

来源：

THYROID | 2007年 / 17卷 / 05期

关键词：

D O I：

10.1089/thy.2007.0032

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Leptin, which is produced by adipocytes, is known to be an important regulator of food intake and energy storage. Disturbance of thyroid function is associated with marked changes in both body weight and energy expenditure, and it has therefore been the subject of much research to study the mutual roles of leptin and thyroid hormones in this respect. Despite intensive research in this field, results are still not very clear. The aim of this review has been to update the current state of knowledge of leptin related to thyroid pathophysiology.

引用

页码：413 / 419

页数：7

共 67 条

[1] Role of leptin in the neuroendocrine response to fasting [J].

Ahima, RS ;

Prabakaran, D ;

Mantzoros, C ;

Qu, DQ ;

Lowell, B ;

MaratosFlier, E ;

Flier, JS .

NATURE, 1996, 382 (6588) :250-252

[2]

Ashworth P, 2005, PROF ENG, V18, P24

[3] Leptin [J].

Auwerx, J ;

Staels, B .

LANCET, 1998, 351 (9104) :737-742

[4] Human and clinical perspectives on leptin [J].

Blum, WF ;

Englaro, P ;

Attanasio, AM ;

Kiess, W ;

Rascher, W .

PROCEEDINGS OF THE NUTRITION SOCIETY, 1998, 57 (03) :477-485

[5] Differential effects of leptin and refeeding on the fasting-induced decrease of pituitary type 2 deiodinase and thyroid hormone receptor β2 mRNA expression in mice [J].

Boelen, A. ;

Kwakkel, J. ;

Vos, X. G. ;

Wiersinga, W. M. ;

Fliers, E. .

JOURNAL OF ENDOCRINOLOGY, 2006, 190 (02) :537-544

[6] Effects of thyroid hormones on serum levels of adipokines as studied in patients with differentiated thyroid carcinoma during thyroxine withdrawal [J].

Botella-Carretero, Jose ;

Alvarez-Blasco, Francisco ;

Sancho, Jose ;

Escobar-Morreale, Hector F. .

THYROID, 2006, 16 (04) :397-402

[7] Free and protein bound leptin are distinct and independently controlled factors in energy regulation [J].

Brabant, G ;

Horn, R ;

von zur Mühlen, A ;

Mayr, B ;

Wurster, U ;

Heidenreich, E ;

Schnabel, D ;

Grüters-Kieslich, A ;

Zimmermann-Belsing, T ;

Feldt-Rasmussen, U .

DIABETOLOGIA, 2000, 43 (04) :438-442

[8]

Breidert M, 1999, SCAND J GASTROENTERO, V34, P954, DOI 10.1080/003655299750025039

[9] The long form of the leptin receptor (OB-Rb) is widely expressed in the human brain [J].

Burguera, B ;

Couce, ME ;

Long, J ;

Lamsam, J ;

Laakso, K ;

Jensen, MD ;

Parisi, JE ;

Lloyd, RV .

NEUROENDOCRINOLOGY, 2000, 71 (03) :187-195

[10] RECOMBINANT MOUSE OB PROTEIN - EVIDENCE FOR A PERIPHERAL SIGNAL LINKING ADIPOSITY AND CENTRAL NEURAL NETWORKS [J].

CAMPFIELD, LA ;

SMITH, FJ ;

GUISEZ, Y ;

DEVOS, R ;

BURN, P .

SCIENCE, 1995, 269 (5223) :546-549

← 1 2 3 4 5 6 7 →