Fresh osteochondral allografting in the treatment of osteochondritis dissecans of the femoral condyle

被引:206
作者
Emmerson, Bryan C.
Gortz, Simon
Jamali, Amir A.
Chung, Christine
Amiel, David
Bugbee, William D.
机构
[1] Univ Calif San Diego, Dept Orthopaed Surg, La Jolla, CA 92093 USA
[2] Univ Calif Davis, Dept Orthopaed Surg, Sacramento, CA 95817 USA
[3] Univ Calif Davis, Dept Radiol, Sacramento, CA 95817 USA
关键词
osteochondritis dissecans; osteochondral defect; fresh osteochondral allograft; osteochondral transplantation; knee cartilage; AUTOLOGOUS CHONDROCYTE IMPLANTATION; ARTICULAR-CARTILAGE; KNEE; DEFECTS; TRANSPLANTATION; MICROFRACTURE; SURVIVAL; GRAFTS;
D O I
10.1177/0363546507299932
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Background: The treatment of osteochondritis dissecans in the adult knee can be challenging. As part of our comprehensive treatment program, fresh osteochondral allografts have been used in the surgical management of osteochondritis dissecans of the femoral condyle. Hypothesis: Fresh osteochondral allograft transplantation will provide a successful surgical treatment for osteochondritis dissecans of the femoral condyle. Study Design: Case series; Level of evidence, 4. Methods: Sixty-six knees in 64 patients underwent fresh osteochondral allografting for the treatment of osteochondritis dissecans. Each patient was evaluated both preoperatively and postoperatively using an 18-point modified D'Aubigne and Postel scale. Subjective assessment was performed using a patient questionnaire. Radiographs were evaluated preoperatively and postoperatively. Results: Mean follow-up was 7.7 years (range, 2-22 years). There were 45 men and 19 women with a mean age of 28.6 years (range, 15-54 years). All patients had undergone previous surgery. Forty-one lesions involved the medial femoral condyle, and 25 involved the lateral femoral condyle. All were osteochondritis dissecans type 3 or 4. The mean allograft size was 7.5 cm(2). One knee was lost to follow-up. Of the remaining 65 knees, 47 (72%) were rated good/excellent, 7 (11 %) were rated fair, and 1 (2%) was rated poor. Ten patients (15%) underwent reoperation. The mean clinical score improved from 13.0 preoperatively to 16.4 postoperatively (P <.01). Fifty-nine of 64 patients completed questionnaires. Subjective knee function improved from a mean of 3.4 to 8.4 on a 10-point scale (P <.01). Conclusion: With greater than 70% good or excellent results, fresh osteochondral allograft transplantation is a successful surgical treatment for osteochondritis dissecans of the femoral condyle.
引用
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页码:907 / 914
页数:8
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