An Update on the Impact of Postnatal Systemic Corticosteroids on Mortality and Cerebral Palsy in Preterm Infants: Effect Modification by Risk of Bronchopulmonary Dysplasia

被引:149
作者
Doyle, Lex W. [1 ,2 ,3 ]
Halliday, Henry L. [4 ]
Ehrenkranz, Richard A. [5 ]
Davis, Peter G. [1 ,2 ,3 ]
Sinclair, John C. [6 ,7 ]
机构
[1] Royal Womens Hosp, Dept Obstet & Gynecol, Parkville, Vic 3052, Australia
[2] Univ Melbourne, Parkville, Vic 3052, Australia
[3] Murdoch Childrens Res Ctr, Parkville, Vic, Australia
[4] Queens Univ Belfast, Dept Child Hlth, Belfast BT7 1NN, Antrim, North Ireland
[5] Yale Univ, Sch Med, Dept Pediat, New Haven, CT 06510 USA
[6] McMaster Univ, Dept Pediat, Hamilton, ON, Canada
[7] McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada
基金
英国医学研究理事会;
关键词
CHRONIC LUNG-DISEASE; EARLY DEXAMETHASONE TREATMENT; EARLY ADRENAL INSUFFICIENCY; PLACEBO-CONTROLLED TRIAL; LOW-DOSE HYDROCORTISONE; BIRTH-WEIGHT INFANTS; FOLLOW-UP; NEURODEVELOPMENTAL OUTCOMES; VENTILATOR DEPENDENCY; PULSE DEXAMETHASONE;
D O I
10.1016/j.jpeds.2014.07.049
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Infants at higher risk of bronchopulmonary dysplasia had increased rates of survival free of cerebral palsy after postnatal corticosteroid treatment in a previous metaregression of data from 14 randomized controlled trials. The relationship persists and is stronger in an updated analysis with data from 20 randomized controlled trials.
引用
收藏
页码:1258 / 1260
页数:3
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