Early clues regarding the pathogenesis of long-COVID

被引:87
作者
Peluso, Michael J. J. [1 ]
Deeks, Steven G. G. [1 ,2 ]
机构
[1] Univ Calif San Francisco, Div HIV Infect Dis & Global Med, San Francisco, CA USA
[2] 1001 Potero Ave, San Francisco, CA 94110 USA
关键词
D O I
10.1016/j.it.2022.02.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Intense investigation into the predictors and determinants of post-acute sequelae of SARS-CoV-2 infection (PASC), including 'long COVID', is underway. Recent studies provide clues to the mechanisms that might drive this condition, with the goal of identifying host or virus factors that can be intervened upon to prevent or reverse PASC.
引用
收藏
页码:268 / 270
页数:3
相关论文
共 10 条
[1]   Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis [J].
Bjornevik, Kjetil ;
Cortese, Marianna ;
Healy, Brian C. ;
Kuhle, Jens ;
Mina, Michael J. ;
Leng, Yumei ;
Elledge, Stephen J. ;
Niebuhr, David W. ;
Scher, Ann, I ;
Munger, Kassandra L. ;
Ascherio, Alberto .
SCIENCE, 2022, 375 (6578) :296-+
[2]   Type I interferon, anti-interferon antibodies, and COVID-19 [J].
Calabrese, Leonard H. ;
Winthrop, Kevin ;
Strand, Vibeke ;
Yazdany, Jinoos ;
Walter, Jolan E. .
LANCET RHEUMATOLOGY, 2021, 3 (04) :E246-E247
[3]   Immunoglobulin signature predicts risk of post-acute COVID-19 syndrome [J].
Cervia, Carlo ;
Zurbuchen, Yves ;
Taeschler, Patrick ;
Ballouz, Tala ;
Menges, Dominik ;
Hasler, Sara ;
Adamo, Sarah ;
Raeber, Miro E. ;
Bachli, Esther ;
Rudiger, Alain ;
Stussi-Helbling, Melina ;
Huber, Lars C. ;
Nilsson, Jakob ;
Held, Ulrike ;
Puhan, Milo A. ;
Boyman, Onur .
NATURE COMMUNICATIONS, 2022, 13 (01)
[4]  
Chertow D., 2021, Res Square, DOI [DOI 10.21203/RS.3.RS-1139035/V1, 10.21203/rs.3.rs-1139035/v1]
[5]   Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome [J].
Liu, Qin ;
Mak, Joyce Wing Yan ;
Su, Qi ;
Yeoh, Yun Kit ;
Lui, Grace Chung-Yan ;
Ng, Susanna So Shan ;
Zhang, Fen ;
Li, Amy Y. L. ;
Lu, Wenqi ;
Hui, David Shu-Cheong ;
Chan, Paul K. S. ;
Chan, Francis K. L. ;
Ng, Siew C. .
GUT, 2022, 71 (03) :544-552
[6]   Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection [J].
Peluso, Michael J. ;
Lu, Scott ;
Tang, Alex F. ;
Durstenfeld, Matthew S. ;
Ho, Hsi-En ;
Goldberg, Sarah A. ;
Forman, Carrie A. ;
Munter, Sadie E. ;
Hoh, Rebecca ;
Tai, Viva ;
Chenna, Ahmed ;
Yee, Brandon C. ;
Winslow, John W. ;
Petropoulos, Christos J. ;
Greenhouse, Bryan ;
Hunt, Peter W. ;
Hsue, Priscilla Y. ;
Martin, Jeffrey N. ;
Kelly, J. Daniel ;
Glidden, David, V ;
Deeks, Steven G. ;
Henrich, Timothy J. .
JOURNAL OF INFECTIOUS DISEASES, 2021, 224 (11) :1839-1848
[7]   Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection [J].
Phetsouphanh, Chansavath ;
Darley, David ;
Wilson, Daniel B. ;
Howe, Annett ;
Munier, C. Mee Ling ;
Patel, Sheila K. ;
Juno, Jennifer A. ;
Burrell, Louise M. ;
Kent, Stephen J. ;
Dore, Gregory J. ;
Kelleher, Anthony D. ;
Matthews, Gail, V .
NATURE IMMUNOLOGY, 2022, 23 (02) :210-+
[8]   Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin [J].
Pretorius, Etheresia ;
Vlok, Mare ;
Venter, Chantelle ;
Bezuidenhout, Johannes A. ;
Laubscher, Gert Jacobus ;
Steenkamp, Janami ;
Kell, Douglas B. .
CARDIOVASCULAR DIABETOLOGY, 2021, 20 (01)
[9]   Persistent Symptoms in Adult Patients 1 Year After Coronavirus Disease 2019 (COVID-19): A Prospective Cohort Study [J].
Seessle, Jessica ;
Waterboer, Tim ;
Hippchen, Theresa ;
Simon, Julia ;
Kirchner, Marietta ;
Lim, Adeline ;
Mueller, Barbara ;
Merle, Uta .
CLINICAL INFECTIOUS DISEASES, 2022, 74 (07) :1191-1198
[10]   Multiple early factors anticipate post-acute COVID-19 sequelae [J].
Su, Yapeng ;
Yuan, Dan ;
Chen, Daniel G. ;
Ng, Rachel H. ;
Wang, Kai ;
Choi, Jongchan ;
Li, Sarah ;
Hong, Sunga ;
Zhang, Rongyu ;
Xie, Jingyi ;
Kornilov, Sergey A. ;
Scherler, Kelsey ;
Pavlovitch-Bedzyk, Ana Jimena ;
Dong, Shen ;
Lausted, Christopher ;
Lee, Inyoul ;
Fallen, Shannon ;
Dai, Chengzhen L. ;
Baloni, Priyanka ;
Smith, Brett ;
Duvvuri, Venkata R. ;
Anderson, Kristin G. ;
Li, Jing ;
Yang, Fan ;
Duncombe, Caroline J. ;
McCulloch, Denise J. ;
Rostomily, Clifford ;
Troisch, Pamela ;
Zhou, Jing ;
Mackay, Sean ;
DeGottardi, Quinn ;
May, Damon H. ;
Taniguchi, Ruth ;
Gittelman, Rachel M. ;
Klinger, Mark ;
Snyder, Thomas M. ;
Roper, Ryan ;
Wojciechowska, Gladys ;
Murray, Kim ;
Edmark, Rick ;
Evans, Simon ;
Jones, Lesley ;
Zhou, Yong ;
Rowen, Lee ;
Liu, Rachel ;
Chour, William ;
Algren, Heather A. ;
Berrington, William R. ;
Wallick, Julie A. ;
Cochran, Rebecca A. .
CELL, 2022, 185 (05) :881-+