The role of local estrogen therapy in the management of pelvic floor disorders

被引：22

作者：

Tzur, T. ^{[1
]}

Yohai, D. ^{[1
]}

Weintraub, A. Y. ^{[1
]}

机构：

[1] Ben Gurion Univ Negev, Dept Obstet & Gynecol, Soroka Univ Med Ctr, Fac Hlth Sci, IL-84105 Beer Sheva, Israel

来源：

CLIMACTERIC | 2016年 / 19卷 / 02期

关键词：

pelvic floor disorders; menopause; Estrogen deficiency; local estrogen therapy; LOWER URINARY-TRACT; LOW-DOSE ESTRADIOL; CONJUGATED EQUINE ESTROGEN; 10; MU-G; POSTMENOPAUSAL WOMEN; VAGINAL ATROPHY; OVERACTIVE BLADDER; GENITOURINARY SYMPTOMS; CONTINENCE SOCIETY; SEXUAL DYSFUNCTION;

D O I：

10.3109/13697137.2015.1132199

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Pelvic floor disorders are common and bothersome problems that include a variety of conditions. These conditions greatly affect the performance of daily activities and social function such as work, traveling, physical exercise, sleep and sexual function. Aging is a well-known factor affecting the pelvic floor and lower urinary tract anatomy and function. It is clear that the pelvic organs and their surrounding muscular and connective tissue support are estrogen-responsive. Treatment of pelvic floor disorders requires significant health-care resources and their impact is likely to increase in the near future. This literature review aims to provide an overview of both research and clinical aspects of the pathophysiology of urogenital estrogen deficiency and the role of local estrogen therapy as part of the management strategy of different pelvic floor disorders. The safety and risk concerns regarding the use of local estrogen therapy are addressed as well.

引用

页码：162 / 171

页数：10

共 98 条

[1] The standardisation of terminology in lower urinary tract function: Report from the standardisation sub-committee of the International Continence Society (Reprinted from Neurourology and Urodynamics, vol 21, pg 167-178, 2002) [J].