Cardiac imageology changes in patients with mild obstructive sleep apnea without cardiovascular disease

Purpose This study aims to assess changes in cardiac imageology of patients with mild obstructive sleep apnea (OSA) without cardiovascular disease. Methods All enrolled participants underwent polysomnography (PSG). Some participants underwent transthoracic echocardiography, speckle tracking echocardiography, and cardiac-enhanced magnetic resonance imaging (MRI) if they were willing. They were divided into three groups according to PSG results: non-OSA, mild OSA, and moderate-to-severe OSA. Imageology parameters were compared, and the relationship between OSA severity and imageology indices was analyzed by correlation analysis and multiple linear regression. Results Of the 352 enrolled participants, 274 participants with OSA had an apnea-hypopnea index (AHI) of >= 5 (86 mild OSA and 188 moderate-to-severe OSA cases), and 78 participants with non-OSA had an AHI of < 5. Transthoracic echocardiography showed that E/A and E'/A' values were lower in the mild OSA group than in the non-OSA group (1.12 +/- 0.37 vs 1.27 +/- 0.45 and 0.83 +/- 0.33 vs 0.99 +/- 0.42, respectively, p < 0.05). The aorta and ascending aorta widths were smaller in the mild OSA group than in the moderate-and-severe OSA groups (27.36 +/- 2.87 mm vs 28.87 +/- 2.95 mm and 30.27 +/- 3.79 mm vs 31.63 +/- 3.74 mm, respectively, p < 0.05). A regression analysis showed that cardiac function changes in patients with OSA may be related to age, obesity, and OSA severity. Conclusion Patients with mild OSA without cardiovascular disease displayed changes in cardiac structure and function on transthoracic echocardiography.