Substantia nigra hyperechogenicity correlates with subtle motor dysfunction in tap dancers

被引：25
作者：
Ruprecht-Doerfler, Petra
Klotz, Patricia
Becker, Georg
Berg, Daniela
机构：
[1] Univ Wurzburg, Dept Neurol, D-8700 Wurzburg, Germany
[2] Univ Wurzburg, Dept Pediat, Wurzburg, Germany
[3] Univ Homburg Saar, Dept Neurol, Homburg, Germany
[4] Univ Tubingen, Inst Med Genet, Tubingen, Germany
[5] Univ Tubingen, Hertie Inst Clin Brain Res, Tubingen, Germany
[6] Hertie Inst Clin Brain Res, D-72076 Tubingen, Germany
来源：
PARKINSONISM & RELATED DISORDERS | 2007年 / 13卷 / 06期
关键词：
nigrostriatal hypofunction; substantia nigra echogenicity; transcranial ultrasound; vulnerability marker;
D O I：
10.1016/j.parkreldis.2006.07.006
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Hyperechogenicity of the substantia nigra (SN) detected by transcranial sonography is a typical finding in more than 90% of patients with Parkinson's disease (PD) but may also be visible in about 9% of healthy adults. In this study, we found a correlation between SN hyperechogenicity and subtle motor dysfunction in otherwise healthy young tap dancers. In accordance with former findings, results of the present study confirm the hypothesis that SN hyperechogenicity is a marker for a possible functional impairment of the nigrostriatal system, that may become evident under challenging conditions. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：362 / 364
页数：3
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