Recent Advances in Functionalization of α-C(sp3)-H Centres in Inactivated Ethers through Cross Dehydrogenative Coupling

被引：58
作者：
Batra, Aanchal [1 ]
Singh, Paramjit [2 ,3 ]
Singh, Kamal Nain [2 ,3 ]
机构：
[1] DAV Coll, Dept Chem, Sec 10-D, Chandigarh, India
[2] Panjab Univ, Dept Chem, Chandigarh 160014, India
[3] Panjab Univ, Ctr Adv Studies Chem, Chandigarh 160014, India
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 2017卷 / 26期
关键词：
Saturated cyclic and acyclic ethers; Cross dehydrogenative coupling; Cross-coupling; C-H activation; C-H activation/ functionalization; C-C; C-X bond formation; Radical reactions; Reaction mechanisms; C-C BOND; DIRECT ALPHA-ARYLATION; C(SP(3))-H BONDS; H BONDS; DIRECT ACCESS; OXIDATIVE ACTIVATION; CINNAMIC-ACIDS; CYCLIC ETHERS; N-OXIDES; AMINATION;
D O I：
10.1002/ejoc.201700341
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Carbon-carbon and carbon-heteroatom bond construction through oxidative carbon-hydrogen bond activation has attracted much attention in synthetic organic chemistry. Recently, a variety of reactions of inactivated cyclic ethers (THF, THP and dioxane) and acyclic ethers with various coupling part-ners have been reported. Despite the absence of phenyl rings and high oxidation potentials, these ethers worked efficiently under oxidative conditions. This review focusses on recent reports of C-C and C-heteroatom bond formation in these cyclic and acyclic ethers through cross dehydrogenative coupling.
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收藏
页码：3739 / 3762
页数：24
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