Ketosis-Prone Type 2 Diabetes: A Case Series

被引:14
作者
Sjoholm, Ake [1 ]
机构
[1] Gavle Cent Hosp, Dept Internal Med, Div Endocrinol & Diabetol, Gavle, Sweden
来源
FRONTIERS IN ENDOCRINOLOGY | 2019年 / 10卷
关键词
atypical diabetes; ketosis; Flatbush diabetes; GLP-1-glucagon-like peptide-1; SGLT; 2; inhibitor; BETA-CELL DYSFUNCTION; INSULIN-SECRETION; NORMOGLYCEMIC REMISSION; INTRAVENOUS GLUCOSE; ATYPICAL TYPE-1; KETOACIDOSIS; NIDDM; CLASSIFICATION; POPULATION; MECHANISM;
D O I
10.3389/fendo.2019.00684
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ketosis-prone type 2 diabetes ("Flatbush diabetes") carries features of both classical type 1 and type 2 diabetes and is highly prevalent in African populations. The disease, which is highly ketosis-prone, but neither chronically insulinopenic nor autoimmune, is discussed regarding pathogenesis, diagnosis and treatment from a patient case perspective.
引用
收藏
页数:7
相关论文
共 49 条
  • [41] Ketosis-prone type 2 diabetes mellitus and human herpesvirus 8 infection in sub-Saharan Africans
    Sobngwi, Eugene
    Choukem, Simeon Pierre
    Agbalika, Felix
    Blondeau, Bertrand
    Fetita, Lila-Sabrina
    Lebbe, Celeste
    Thiam, Doudou
    Cattan, Pierre
    Larghero, Jerome
    Foufelle, Fabienne
    Ferre, Pascal
    Vexiau, Patrick
    Calvo, Fabien
    Gautier, Jean-Francois
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 299 (23): : 2770 - 2776
  • [42] Approach to the patient with atypical diabetes
    Steenkamp, Devin W.
    Alexanian, Sara M.
    Sternthal, Elliot
    [J]. CANADIAN MEDICAL ASSOCIATION JOURNAL, 2014, 186 (09) : 678 - 684
  • [43] Narrative review: Ketosis-prone type 2 diabetes mellitus
    Umpierrez, GE
    Smiley, D
    Kitabchi, AE
    [J]. ANNALS OF INTERNAL MEDICINE, 2006, 144 (05) : 350 - 357
  • [44] Lack of Lipotoxicity Effect on β-Cell Dysfunction in Ketosis-Prone Type 2 Diabetes
    Umpierrez, Guillermo E.
    Smiley, Dawn
    Robalino, Gonzalo
    Peng, Limin
    Gosmanov, Aidar R.
    Kitabchi, Abbas E.
    [J]. DIABETES CARE, 2010, 33 (03) : 626 - 631
  • [45] Randomized Controlled Study of Metformin and Sitagliptin on Long-term Normoglycemia Remission in African American Patients With Hyperglycemic Crises
    Vellanki, Priyathama
    Smiley, Dawn D.
    Stefanovski, Darko
    Anzola, Isabel
    Duan, Wenlan
    Hudson, Megan
    Peng, Limin
    Pasquel, Francisco J.
    Umpierrez, Guillermo E.
    [J]. DIABETES CARE, 2016, 39 (11) : 1948 - 1955
  • [46] Ketoacidosis occurs in both Type 1 and Type 2 diabetes - a population-based study from Northern Sweden
    Wang, Z. H.
    Kihl-Selstam, E.
    Eriksson, J. W.
    [J]. DIABETIC MEDICINE, 2008, 25 (07) : 867 - 870
  • [47] Towards better understanding of the contributions of overwork and glucotoxicity to the β-cell inadequacy of type 2 diabetes
    Weir, G. C.
    Marselli, L.
    Marchetti, P.
    Katsuta, H.
    Jung, M. H.
    Bonner-Weir, S.
    [J]. DIABETES OBESITY & METABOLISM, 2009, 11 : 82 - 90
  • [48] Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes
    Yang, Yisheng
    Chan, Lawrence
    [J]. ENDOCRINE REVIEWS, 2016, 37 (03) : 190 - 222
  • [49] LONG-TERM EXPOSURE TO FATTY-ACIDS AND KETONES INHIBITS B-CELL FUNCTIONS IN HUMAN PANCREATIC-ISLETS OF LANGERHANS
    ZHOU, YP
    GRILL, V
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1995, 80 (05) : 1584 - 1590