Ketosis-Prone Type 2 Diabetes: A Case Series

被引:14
作者
Sjoholm, Ake [1 ]
机构
[1] Gavle Cent Hosp, Dept Internal Med, Div Endocrinol & Diabetol, Gavle, Sweden
来源
FRONTIERS IN ENDOCRINOLOGY | 2019年 / 10卷
关键词
atypical diabetes; ketosis; Flatbush diabetes; GLP-1-glucagon-like peptide-1; SGLT; 2; inhibitor; BETA-CELL DYSFUNCTION; INSULIN-SECRETION; NORMOGLYCEMIC REMISSION; INTRAVENOUS GLUCOSE; ATYPICAL TYPE-1; KETOACIDOSIS; NIDDM; CLASSIFICATION; POPULATION; MECHANISM;
D O I
10.3389/fendo.2019.00684
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ketosis-prone type 2 diabetes ("Flatbush diabetes") carries features of both classical type 1 and type 2 diabetes and is highly prevalent in African populations. The disease, which is highly ketosis-prone, but neither chronically insulinopenic nor autoimmune, is discussed regarding pathogenesis, diagnosis and treatment from a patient case perspective.
引用
收藏
页数:7
相关论文
共 49 条
  • [21] Genetics of diabetes - Are we missing the genes or the disease?
    Groop, Leif
    Pociot, Flemming
    [J]. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2014, 382 (01) : 726 - 739
  • [22] ANTIDIABETOGENIC EFFECT OF GLUCAGON-LIKE PEPTIDE-1 (7-36)AMIDE IN NORMAL SUBJECTS AND PATIENTS WITH DIABETES-MELLITUS
    GUTNIAK, M
    ORSKOV, C
    HOLST, JJ
    AHREN, B
    EFENDIC, S
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (20) : 1316 - 1322
  • [23] PANCREATIC BETA-CELLS ARE RENDERED GLUCOSE-COMPETENT BY THE INSULINOTROPIC HORMONE GLUCAGON-LIKE PEPTIDE-1(7-37)
    HOLZ, GG
    KUHTREIBER, WM
    HABENER, JF
    [J]. NATURE, 1993, 361 (6410) : 362 - 365
  • [24] Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
    Kahn, Steven E.
    Haffner, Steven M.
    Heise, Mark A.
    Herman, William H.
    Holman, Rury R.
    Jones, Nigel P.
    Kravitz, Barbara G.
    Lachin, John M.
    O'Neill, M. Colleen
    Zinman, Bernard
    Viberti, Giancarlo
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (23) : 2427 - 2443
  • [25] The spectrum of clinical presentation, diagnosis, and management of mitochondrial forms of diabetes
    Karaa, Amel
    Goldstein, Amy
    [J]. PEDIATRIC DIABETES, 2015, 16 (01) : 1 - 9
  • [26] Editorial: Ketosis-prone diabetes - A new subgroup of patients with atypical type 1 and type 2 diabetes?
    Kitabchi, AE
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (11) : 5087 - 5089
  • [27] Mitochondrial diabetes - Molecular mechanisms and clinical presentation
    Maassen, JA
    't Hart, LM
    van Essen, E
    Heine, RJ
    Nijpels, G
    Tafrechi, RSJ
    Raap, AK
    Janssen, GMC
    Lemkes, HHPJ
    [J]. DIABETES, 2004, 53 : S103 - S109
  • [28] Mitochondrial function in normal and diabetic β-cells
    Maechler, P
    Wollheim, CB
    [J]. NATURE, 2001, 414 (6865) : 807 - 812
  • [29] Sulfonylurea induced β-cell apoptosis in cultured human islets
    Maedler, K
    Carr, RD
    Bosco, D
    Zuellig, RA
    Berney, T
    Donath, MY
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (01) : 501 - 506
  • [30] Ketosis-prone diabetes:: Dissection of a heterogeneous syndrome using an immunogenetic and β-cell functional classification, prospective analysis, and clinical outcomes
    Maldonado, M
    Hampe, CS
    Gaur, LK
    D'Amico, S
    Iyer, D
    Hammerle, LP
    Bolgiano, D
    Rodriguez, L
    Rajan, A
    Lernmark, Å
    Balasubramanyam, A
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (11) : 5090 - 5098