Serum antimullerian hormone (AMH) levels are elevated in adolescent girls with polycystic ovaries and the polycystic ovarian syndrome (PCOS)

被引：112
作者：
Hart, Roger [1 ,2 ]
Doherty, Dorota A. [1 ,2 ]
Norman, Robert J. [3 ]
Franks, Stephen [4 ]
Dickinson, Jan E. [1 ]
Hickey, Martha [1 ]
Sloboda, Deborah M. [5 ,6 ]
机构：
[1] Univ Western Australia, Sch Womens & Infants Hlth, Perth, WA 6009, Australia
[2] King Edward Mem Hosp, Women & Infants Res Fdn, Perth, WA 6008, Australia
[3] Univ Adelaide, Sch Paediat & Reprod Hlth, Res Ctr Reprod Hlth, Robinson Inst, Adelaide, SA, Australia
[4] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Inst Reprod & Dev Biol, London, England
[5] Univ Auckland, Liggins Inst, Auckland 1, New Zealand
[6] Natl Res Ctr Growth & Dev, Auckland, New Zealand
来源：
FERTILITY AND STERILITY | 2010年 / 94卷 / 03期
基金：
英国医学研究理事会;
关键词：
ANTI-MULLERIAN HORMONE; MENSTRUAL-CYCLE; WOMEN; PREVALENCE; ULTRASOUND; FEATURES; AGE;
D O I：
10.1016/j.fertnstert.2009.11.002
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in adolescents, with potentially significant lifelong consequences. This prospective study set out to determine if the investigators could derive a threshold value of antimullerian hormone (AMH) that would predict its presence according to two internationally recognized definitions using a simple measurement, avoiding more extensive and potentially more invasive investigations. The study failed to demonstrate, in a general adolescent population, that serum AMH is a reliable predictor of PCO morphology or for the presence of PCOS. (Fertil Steril (R) 2010;94:1118-21. (C)2010 by American Society for Reproductive Medicine.)
引用
收藏
页码：1118 / 1121
页数：4
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