Thyroid hormones in HIV-infected patients in the highly active antiretroviral therapy era: evidence of an interrelation between the thyroid axis and the immune system

被引:37
作者
Collazos, J [1 ]
Ibarra, S [1 ]
Mayo, J [1 ]
机构
[1] Hosp Galdakao, Infect Dis Sect, Vizcaya, Spain
关键词
D O I
10.1097/00002030-200303280-00019
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In a total of 372 determinations of thyroid hormones in HIV-infected patients we found a correlation between free thyroxine and CD4 cell counts, which was maintained after stratification by CD4 cell count and therapeutic groups, and was confirmed by multivariate analysis. Patients with normal free thyroxine had higher CD4 cell counts than those with low free thyroxine. Anti-retroviral drugs did not influence free thyroxine levels. Our results support an interrelationship between the thyroid axis and the immune system.
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页码:763 / 765
页数:3
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