Three cases of pityriasis rubra pilaris successfully treated with cyclosporin A

被引:20
作者
Usuki, K [1 ]
Sekiyama, M [1 ]
Shimada, T [1 ]
Shimada, S [1 ]
Kanzaki, T [1 ]
机构
[1] Kagoshima Univ, Fac Med, Dept Dermatol, Kagoshima 8908520, Japan
关键词
pityriasis rubra pilaris; cyclosporin A; immunosuppressive agent;
D O I
10.1159/000018397
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Pityriasis rubra pilaris (PRP) is reported to respond poorly to cyclosporin A (CsA), Objective: We attempted to deter mine the efficacy of CsA in the treatment of classic adult-type PRP, Methods: Three patients with classic adult-type PRP were treated with 5 mg/kg/day CsA, Results: A sustained clinical response was achieved within 2-4 weeks of therapy. Relapses were noted when the CsA dose was decreased to 1.2 mg/kg/day. Conclusion: CsA should be considered in the treatment of classical adult-type PRP. Copyright (C) 2000 S. Karger AG, Baser.
引用
收藏
页码:324 / 327
页数:4
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