Outcomes and toxicities of re-irradiation for prostate cancer: A systematic review on behalf of the Re-Irradiation Working Group of the Italian Association of Radiotherapy and Clinical Oncology (AIRO)

被引：22

作者：

Munoz, Fernando ^{[1
]}

Fiorica, Francesco ^{[2
]}

Caravatta, Luciana ^{[3
]}

Rosa, Consuelo ^{[3
]}

Ferella, Letizia ^{[1
]}

Boldrini, Luca ^{[4
]}

Fionda, Bruno ^{[4
]}

Alitto, Anna Rita ^{[4
]}

Nardangeli, Alessia ^{[4
]}

Dionisi, Francesco ^{[5
]}

Arcangeli, Stefano ^{[6
,7
]}

Di Marzo, Alessandro ^{[8
]}

Pontoriero, Antonio ^{[9
]}

Donato, Vittorio ^{[10
]}

Massaccesi, Mariangela ^{[4
]}

机构：

[1] Parini Hosp, Radiotherapy Unit, Viale Ginevra 3, I-11100 Aosta, Italy

[2] State Hosp Mater Salutis AULSS 9, Dept Radiat Oncol & Nucl Med, Via Carlo Gianella 1, I-37045 Legnago, VR, Italy

[3] Univ G dAnnunzio, SS Annunziata Hosp, Radiat Oncol Unit, Via Vestini, I-66100 Chieti, Italy

[4] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli, Dept Radiol Radiotherapy & Hematol Sci, Via Pineta Sacchetti 217, I-00168 Rome, Italy

[5] APSS, Proton Therapy Unit, Dept Oncol, Via Alcide Degasperi 79, I-38123 Trento, Italy

[6] Policlin S Gerardo, Dept Radiat Oncol, Via Sansovino 4, I-20133 Milan, Italy

[7] Univ Milano Bicocca, Via Sansovino 4, I-20133 Milan, Italy

[8] S Maria Hosp, Radiotherapy Oncol Ctr, Viale Tristano Joannuccio, I-05100 Terni, Italy

[9] Univ Hosp G Martino, Dept Image Diagnost, Operat Unit Radiat Oncol, Messina, Italy

[10] Azienda Osped San Camillo Forlanini, Radiat Oncol, Circonvallaz Gianicolense 87, I-00152 Rome, Italy

来源：

CANCER TREATMENT REVIEWS | 2021年 / 95卷

关键词：

Cumulative dose; Outcomes; Prostate cancer; Re-irradiation; Toxicity; DOSE-RATE BRACHYTHERAPY; BEAM RADIATION-THERAPY; SALVAGE BRACHYTHERAPY; RECURRENCE; FAILURE;

D O I：

10.1016/j.ctrv.2021.102176

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aims: The best therapeutic approach for local relapses of previously irradiated prostate cancer (PC) is still not defined. Re-irradiation (Re-I) could offer a chance of cure for highly selected patients, although high quality evidences are lacking. The aim of our study is to provide a literature review on efficacy and safety of Re-I. Methods: Only studies where Re-I field overlaps with previous radiotherapy were considered. To determine 2 and 4 years overall mortality (OM), 2 and 4 years biochemical failure (BF) and pooled acute and late G 0.001). The pooled result of G 0.001). One hundred and three G 3 late adverse events were reported, with a pooled result of G > 3 late toxicity of 8.7% (95%CI: 5.8?13%, P < 0.001). Conclusions: Re-I of local failures from PC showed promising OM and biochemical control rates with a safe toxicity profile.

引用

页数：10

共 72 条

[1] ABUSARIS H, 2012, BRACHYTHERAPY, V11, P591
[2] Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancer
Afshar-Oromieh, Ali
Zechmann, Christian M.
Malcher, Anna
Eder, Matthias
Eisenhut, Michael
Linhart, Heinz G.
Holland-Letz, Tim
Hadaschik, Boris A.
Giesel, Frederik L.
Debus, Juergen
Haberkorn, Uwe
[J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2014, 41 (01) : 11 - 20
[3] ALONGI F, 2013, J UROLOGY, V88, P550, DOI DOI 10.1016/J.CRITREVONC.2013.07.009
[4] [Anonymous], 2019, NCCN CLIN PRACTICE G
[5] Salvage Low Dose Rate Brachytherapy For Recurrent Prostate Cancer After External Beam Radiotherapy: Results From A Single Institution With Focus On Toxicity And Functional Outcomes
Barbera, F.
Triggiani, L.
Buglione, M.
Ghirardelli, P.
Vitali, P.
Caraffini, B.
Borghetti, P.
Greco, D.
Bardoscia, L.
Pasinetti, N.
Costa, L.
Maddalo, M.
Ghedi, B.
La Face, B.
Magrini, S. M.
[J]. CLINICAL MEDICINE INSIGHTS-ONCOLOGY, 2017, 11
[6] Salvage reirradiation for local prostate cancer recurrence after I radiation therapy. For who? When? How?
Baty, M.
Crehange, G.
Pasquier, D.
Palard, X.
Deleuze, A.
Gnep, K.
Key, S.
Beuzit, L.
Castelli, J.
de Crevoisier, R.
[J]. CANCER RADIOTHERAPIE, 2019, 23 (6-7): : 541 - 558
[7] Salvage of locally recurrent prostate cancer after external beam radiation using reduced-dose brachytherapy with neoadjuvant plus adjuvant androgen deprivation
Baumann, Brian C.
Baumann, John C.
Christodouleas, John P.
Soffen, Edward
[J]. BRACHYTHERAPY, 2017, 16 (02) : 291 - 298
[8] Caravatta L, 2020, STRAHLENTHER ONKOL, V196, P1, DOI 10.1007/s00066-019-01519-5
[9] CARLOS V, 2014, INT J RADIAT ONCOL, V13, P53, DOI DOI 10.1016/J.BRACHY.2013.10.012
[10] Chatzikonstantinou G, 2017, STRAHLENTHER ONKOL, V193, P683, DOI 10.1007/s00066-017-1157-2

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