Role of Rock 1 protein in non-small cell lung cancer

被引：0
|
作者：
Yan, Shao-hua [1 ]
Gao, Hai-Cheng [1 ]
Meng, He-yu [3 ]
Cheng, Long [2 ]
Zhe, Lv [1 ]
Cao, Guo-shen [4 ]
Yan, Wei-qun [1 ]
Xin, Hua [2 ]
机构：
[1] Jilin Univ, Dept Clin Pharm, Sch Pharmaceut Sci, Changchun, Peoples R China
[2] Jilin Univ, Dept Cardiol & Chest Surg, China Japan Friendship Hosp, Changchun, Peoples R China
[3] Yanbian Univ, Med Coll, Yanbian, Peoples R China
[4] China Med Univ, Shenyang, Peoples R China
来源：
BIOMEDICAL RESEARCH-INDIA | 2017年 / 28卷 / 06期
关键词：
Rock; 1; NSCLC; Squamous cell carcinoma; Adenocarcinoma; TUMOR-CELLS; EXPRESSION; INVASION; RHO; ANGIOGENESIS; METASTASIS; PATHWAY; GROWTH;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The effects of Rock 1 in non-small cell lung cancer and the relationship between Rock 1 and non-small cell lung cancer were investigated in this study. Sixty cases of non-small cell lung cancer were investigated for the relationship between Rock 1 and non-small cell lung cancer. Expression of Rock 1 in non-small cell lung cancer was detected by histochemical staining and Real-time PCR. All the sixty cases had been diagnosed as non-small lung cancer by CT and HE staining. The expression of Rock 1 in nonsmall cell lung cancer was significantly higher than the adjacent tissues (p<0.05). Positive expression of Rock 1 was 73.33% in 60 cases. Among them, Positive expression of Rock 1 was 71.79% in squamous cell carcinoma of 39 cases. Positive expression of Rock 1 was 76.19% in adenocarcinoma of 21 cases. The expression of Rock1 may be positively related to the lung cancer, suggesting that Rock 1 play an important role in non-small cell lung cancer.
引用
收藏
页码：2530 / 2534
页数：5
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