p53: Emergency brake and target for cancer therapy

被引：26
作者：
Wiman, KG [1 ]
机构：
[1] Karolinska Inst, Ctr Microbiol & Tumor Biol, S-17177 Stockholm, Sweden
来源：
EXPERIMENTAL CELL RESEARCH | 1997年 / 237卷 / 01期
关键词：
D O I：
10.1006/excr.1997.3834
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：14 / 18
页数：5
相关论文
共 39 条
  • [1] Abarzua P, 1996, ONCOGENE, V13, P2477
  • [2] INDUCTION OF THE GROWTH INHIBITOR IGF-BINDING PROTEIN-3 BY P53
    BUCKBINDER, L
    TALBOTT, R
    VELASCOMIGUEL, S
    TAKENAKA, I
    FAHA, B
    SEIZINGER, BR
    KLEY, N
    [J]. NATURE, 1995, 377 (6550) : 646 - 649
  • [3] GROWTH-FACTOR MODULATION OF P53-MEDIATED GROWTH ARREST VERSUS APOPTOSIS
    CANMAN, CE
    GILMER, TM
    COUTTS, SB
    KASTAN, MB
    [J]. GENES & DEVELOPMENT, 1995, 9 (05) : 600 - 611
  • [4] p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    Chen, XB
    Ko, LJ
    Jayaraman, L
    Prives, C
    [J]. GENES & DEVELOPMENT, 1996, 10 (19) : 2438 - 2451
  • [5] WAF1, A POTENTIAL MEDIATOR OF P53 TUMOR SUPPRESSION
    ELDEIRY, WS
    TOKINO, T
    VELCULESCU, VE
    LEVY, DB
    PARSONS, R
    TRENT, JM
    LIN, D
    MERCER, WE
    KINZLER, KW
    VOGELSTEIN, B
    [J]. CELL, 1993, 75 (04) : 817 - 825
  • [6] GREENBLATT MS, 1994, CANCER RES, V54, P4855
  • [7] Synergistic activation of transcription by CBP and p53
    Gu, W
    Shi, XL
    Roeder, RG
    [J]. NATURE, 1997, 387 (6635) : 819 - 823
  • [8] Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
    Gu, W
    Roeder, RG
    [J]. CELL, 1997, 90 (04) : 595 - 606
  • [9] WILD-TYPE P53 ADOPTS A MUTANT-LIKE CONFORMATION WHEN BOUND TO DNA
    HALAZONETIS, TD
    DAVIS, LJ
    KANDIL, AN
    [J]. EMBO JOURNAL, 1993, 12 (03) : 1021 - 1028
  • [10] P53 - AT THE CROSSROADS OF MOLECULAR CARCINOGENESIS AND RISK ASSESSMENT
    HARRIS, CC
    [J]. SCIENCE, 1993, 262 (5142) : 1980 - 1981
1234