INFECTIOUS COMPLICATIONS AND THEIR CONTRIBUTING RISK FACTORS AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

被引：1
作者：
Akhmedov, M., I [1 ]
Klyasova, G. A. [2 ]
Parovichnikova, E. N. [3 ]
机构：
[1] Natl Res Ctr Hematol, Dept Intens Chemotherapy & BMT, Moscow 125167, Russia
[2] Natl Res Ctr Hematol, Lab Clin Microbiol Mycol & Antibiot Therapy, Moscow 125167, Russia
[3] Natl Res Ctr Hematol, Moscow 125167, Russia
来源：
GEMATOLOGIYA I TRANSFUZIOLOGIYA | 2022年 / 67卷 / 01期
关键词：
infections; allogeneic hematopoietic stem cell transplantation; risk factors; bloodstream infections; BLOOD-STREAM INFECTIONS; BONE-MARROW-TRANSPLANTATION; VERSUS-HOST-DISEASE; PERIPHERAL-BLOOD; PRE-ENGRAFTMENT; UNRELATED DONOR; ADULT PATIENTS; RECIPIENTS; BACTEREMIA; BACTERIAL;
D O I：
10.35754/0234-5730-2022-67-1-90-107
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction. Infections are among the most common complications after allogeneic hematopoietic stem cell transplantation. Aim - to provide a literature review on the main characteristics of infectious complications after allogenic hematopoietic stem cell transplantation and risk factors for their development. Main findings. Apart from direct factors such as neutropenia, hypogammaglobulinemia, and lymphopenia, there are indirect transplant-related factors such as conditioning regimen, transplant source, donor type, and graft-versus-host disease prophylaxis associated with higher infectious risk posttransplant. This review also presents the main characteristics of infections after allogeneic hematopoietic stem cell transplantation with a focus on bloodstream infections and provides an overview of the main transplant-related risk factors linked to their development.
引用
收藏
页码：90 / 107
页数：18
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