Severe Diffuse Duodenitis Successfully Treated with Intravenous Tacrolimus after Colectomy for Ulcerative Colitis

被引:7
作者
Saito, Keiko [1 ]
Katsuno, Tatsuro [1 ]
Nakagawa, Tomoo [1 ]
Minemura, Shoko [1 ]
Oyamada, Arata [1 ]
Kanogawa, Naoya [1 ]
Saito, Masaya [1 ]
Yoshihama, Sayuri [1 ]
Maruoka, Daisuke [1 ]
Matsumura, Tomoaki [1 ]
Arai, Makoto [1 ]
Tohma, Takayuki [2 ]
Miyauchi, Hideaki [2 ]
Matsubara, Hisahiro [2 ]
Yokosuka, Osamu [1 ]
机构
[1] Chiba Univ, Grad Sch Med, Dept Gastroenterol & Nephrol K1, Chiba, Japan
[2] Chiba Univ, Grad Sch Med, Dept Frontier Surg M9, Chiba, Japan
关键词
ulcerative colitis; proctocolectomy; duodenitis; double-balloon enteroscopy; tacrolimus; GASTRODUODENITIS; ENTERITIS; PATIENT;
D O I
10.2169/internalmedicine.53.1910
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We encountered a rare case of severe diffuse duodenitis associated with ulcerative colitis (UC). A 23-year-old man underwent total proctocolectomy with ileal J-pouch anal anastomosis for UC. He suffered from severe abdominal pain, fever and bloody diarrhea for six months after the surgery. Upper double-balloon enteroscopy disclosed severe diffuse duodenitis, of which the findings were endoscopically and histologically similar to those of colonic lesions of UC. Although the administration of prednisolone was ineffective, treatment with intravenous tacrolimus markedly improved the clinical findings. This is the first report of the successful treatment of severe UC-associated diffuse duodenitis with intravenous tacrolimus.
引用
收藏
页码:2477 / 2481
页数:5
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