Erythrina studies, part 51.: Isoprenylated flavonoids from the stem bark of Erythrina abyssinica

被引：42

作者：

Cui, Long

Ndinteh, Derek Tantoh

Na, MinKyun

Thuong, Phuong Thien

Silike-Muruumu, John

Njamen, Dieudonne

Mbafor, Joseph Tanyi

Fomurn, Zacharias Tanee

Ahn, Jong Seog

Oh, Won Keun

机构：

[1] KRIBB, Taejon 305806, South Korea

[2] Univ Yaounde I, Fac Sci, Yaounde, Cameroon

[3] Makerere Univ, Kampala, Uganda

[4] Chosun Univ, Coll Pharm, Kwangju 501759, South Korea

来源：

JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 06期

关键词：

D O I：

10.1021/np060477+

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new prenylated flavanones, abyssinoflavanones V, VI, and VII (1- 3), together with eight known flavanones (4- 11) and two chalcones (12- 13), were isolated from the stem bark of Erythrina abyssinica. Their structures were elucidated on the basis of spectroscopic and physicochemical analyses. All the isolates, with the exception of 1 and 8, strongly inhibited PTP1B activity in an in Vitro assay with IC50 values ranging from 14.2 +/- 1.7 to 26.7 +/- 1.2 mu M.

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页码：1039 / 1042

页数：4

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