Microwave-enhanced cadogan cyclization: An easy access to the 2-substituted carbazoles and other fused heterocyclic systems

被引:79
作者
Appukkuttan, P [1 ]
Van der Eycken, E [1 ]
Dehaen, W [1 ]
机构
[1] Katholieke Univ Leuven, Dept Chem, B-3001 Louvain, Belgium
关键词
microwave-enhanced; Suzuki-Miyaura cross-coupling reaction; cadogan reductive cyclization;
D O I
10.1055/s-2004-836030
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A microwave-enhanced Suzuki-Miyaura cross-coupling reaction in combination with a microwave-assisted Cadogan reductive cyclization is presented as an easy access to a variety of 2-substituted carbazoles and other fused heterocyclic systems. Microwave irradiation was found very useful in minimizing the proto-deboronation issues in the cross-coupling reaction, and enhances the rate of reductive cyclization in a dramatic manner.
引用
收藏
页码:127 / 133
页数:7
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