Regulation of human osteoclast differentiation by thioredoxin binding protein-2 and redox-sensitive signaling

被引：37
作者：
Aitken, CJ
Hodge, JM
Nishinaka, Y
Vaughan, T
Yodoi, JJ
Day, CJ
Morrison, NA
Nicholson, GC [1 ]
机构：
[1] Univ Melbourne, Geelong Hosp, Dept Clin & Biomed Sci, Barwon Hlth, Geelong, Vic 3220, Australia
[2] Natl Inst Adv Ind Sci & Technol, Human Stress Signal Res Ctr, Biomed Special Res Unit, Osaka, Japan
[3] Griffith Univ, Sch Hlth Sci, Nathan, Qld 4111, Australia
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 12期
关键词：
osteoclast; thioredoxin binding protein-2; thioredoxin-1; redox; activator protein 1;
D O I：
10.1359/JBMR.040913
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Differential expression of TBP-2 and Trx-1 occurs during osteoclastogenesis. Adenoviral overexpression of TBP-2 in osteoclast precursors inhibits Trx-1 expression, osteoclast formation, and AP-1 binding activity. TBP-2 and Trx-1 are key regulators of osteoclastogenesis.
引用
收藏
页码：2057 / 2064
页数：8
相关论文
共 53 条
  • [1] Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line
    Armstrong, JS
    Steinauer, KK
    Hornung, B
    Irish, JM
    Lecane, P
    Birrell, GW
    Peehl, DM
    Knox, SJ
    [J]. CELL DEATH AND DIFFERENTIATION, 2002, 9 (03) : 252 - 263
  • [2] Association between oxidative stress and bone mineral density
    Basu, S
    Michaëlsson, K
    Olofsson, H
    Johansson, S
    Melhus, H
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 288 (01) : 275 - 279
  • [3] STIMULATION OF OSTEOCLASTIC BONE-RESORPTION BY HYDROGEN-PEROXIDE
    BAX, BE
    ALAM, ASMT
    BANERJI, B
    BAX, CMR
    BEVIS, PJR
    STEVENS, CR
    MOONGA, BS
    BLAKE, DR
    ZAIDI, M
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 183 (03) : 1153 - 1158
  • [4] The free radical theory of aging matures
    Beckman, KB
    Ames, BN
    [J]. PHYSIOLOGICAL REVIEWS, 1998, 78 (02) : 547 - 581
  • [5] Positional cloning of the combined hyperlipidemia gene Hyplip1
    Bodnar, JS
    Chatterjee, A
    Castellani, LW
    Ross, DA
    Ohmen, J
    Cavalcoli, J
    Wu, CY
    Dains, KM
    Catanese, J
    Chu, M
    Sheth, SS
    Charugundla, K
    Demant, P
    West, DB
    de Jong, P
    Lusis, AJ
    [J]. NATURE GENETICS, 2002, 30 (01) : 110 - 116
  • [6] Osteoclast differentiation and activation
    Boyle, WJ
    Simonet, WS
    Lacey, DL
    [J]. NATURE, 2003, 423 (6937) : 337 - 342
  • [7] ISOLATION AND CHARACTERIZATION OF A NOVEL CDNA FROM HL-60 CELLS TREATED WITH 1,25-DIHYDROXYVITAMIN D-3
    CHEN, KS
    DELUCA, HF
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1994, 1219 (01): : 26 - 32
  • [8] Free radicals in the physiological control of cell function
    Dröge, W
    [J]. PHYSIOLOGICAL REVIEWS, 2002, 82 (01) : 47 - 95
  • [9] Redox regulation of NF-kappa B activation
    Flohe, L
    Brigelius-Flohe, R
    Saliou, C
    Traber, MG
    Packer, L
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1997, 22 (06) : 1115 - 1126
  • [10] Hydrogen peroxide, but not superoxide, stimulates bone resorption in mouse calvariae
    Fraser, JHE
    Helfrich, MH
    Wallace, HM
    Ralston, SH
    [J]. BONE, 1996, 19 (03) : 223 - 226
123456