DNA-based barcodes, nanoparticles, and nanostructures for the ultrasensitive detection and quantification fo proteins

被引：54
作者：
Brakmann, S [1 ]
机构：
[1] Univ Leipzig, Inst Biol 2, D-04103 Leipzig, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 43期
关键词：
antibodies; antigens; immunoassays; proteins;
D O I：
10.1002/anie.200461112
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Beyond the shadow of a doubt: Detecting antigens, antibodies, pathogens, tumor markers, and potential therapeutics on the femto- to attomolar concentration level is still challenging. Nanostructured materials and the innovative combination of immunoassays with (real-time) PCR and magnetic separation techniques hold promise for the field of ultrasensitive protein analytics.
引用
收藏
页码：5730 / 5734
页数：5
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