Signalling pathways - Kinase regulation in inflammatory response

被引:109
作者
Delhase, M [1 ]
Li, NX [1 ]
Karin, M [1 ]
机构
[1] Univ Calif San Diego, Lab Gene Regulat & Signal Transduct, La Jolla, CA 92093 USA
关键词
D O I
10.1038/35019154
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
[No abstract available]
引用
收藏
页码:367 / 368
页数:2
相关论文
共 12 条
[1]   An essential role for NF-kappa B in preventing TNF-alpha-induced cell death [J].
Beg, AA ;
Baltimore, D .
SCIENCE, 1996, 274 (5288) :782-784
[2]   Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation [J].
Delhase, M ;
Hayakawa, M ;
Chen, Y ;
Karin, M .
SCIENCE, 1999, 284 (5412) :309-313
[3]   Signal transduction - Akt signaling: Linking membrane events to life and death decisions [J].
Hemmings, BA .
SCIENCE, 1997, 275 (5300) :628-630
[4]   Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase [J].
Hu, YL ;
Baud, V ;
Delhase, M ;
Zhang, PL ;
Deerinck, T ;
Ellisman, M ;
Johnson, R ;
Karin, M .
SCIENCE, 1999, 284 (5412) :316-320
[5]   Severe liver degeneration in mice lacking the IκB kinase 2 gene [J].
Li, QT ;
Van Antwerp, D ;
Mercurio, F ;
Lee, KF ;
Verma, IM .
SCIENCE, 1999, 284 (5412) :321-325
[6]   Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappa B activation prevents cell death [J].
Liu, ZG ;
Hsu, HL ;
Goeddel, DV ;
Karin, M .
CELL, 1996, 87 (03) :565-576
[7]   Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB [J].
Madrid, LV ;
Wang, CY ;
Guttridge, DC ;
Schottelius, AJG ;
Baldwin, AS ;
Mayo, MW .
MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (05) :1626-1638
[8]  
Ozes ON, 1999, NATURE, V401, P82
[9]  
ROTHWARF DM, 1999, NF KAPPA ACTIVATION
[10]  
Sizemore N, 1999, MOL CELL BIOL, V19, P4798