Behcet's disease

被引：29

作者：

Kurokawa, MS

Yoshikawa, H

Suzuki, N

机构：

[1] St Marianna Univ, Sch Med, Dept Immunol, Miyamae Ku, Kawasaki, Kanagawa 2168511, Japan

[2] St Marianna Univ, Sch Med, Dept Med, Miyamae Ku, Kawasaki, Kanagawa 2168511, Japan

来源：

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE | 2004年 / 25卷 / 05期

关键词：

Behcet's disease; pulmonary vasculitis; pulmonary arterial aneurysms; hemoptysis; thrombosis;

D O I：

10.1055/s-2004-836147

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Behcet's disease (BD) is a systemic disorder characterized by recurrent attacks of acute inflammation. Major symptoms are oral aphthous ulcers, uveitis, skin lesions, and genital ulcerations. Involvement of vessels, gastrointestinal (GI) tract, and central nervous system (CNS) is less frequent but is associated with a poor prognosis. Pulmonary complications of BD include aneurysms of the aorta, great vessels, or pulmonary arteries; arterial or venous thrombosis; pulmonary parenchymal changes; pleurisy, and intracardiac thrombosis. Hemoptysis caused by pulmonary artery aneurysms may lead to lethal hemorrhage. Recent advances in therapeutic strategies have improved the prognosis. In this review, the salient clinical and histopathological features of BD and treatment strategies are discussed.

引用

页码：557 / 568

页数：12

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