Toxin structure: Part of a hole?

被引:44
作者
Bayley, H
机构
关键词
D O I
10.1016/S0960-9822(06)00399-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The structure of the monomeric form of perfringolysin O solved by X-ray crystallography has been used to model the very large transmembrane pore formed when this bacterial protein toxin assembles in cholesterol-containing membranes. The structure is a notable advance, but it may not provide the whole story.
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页码:R763 / R767
页数:5
相关论文
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