Economic Burden of Hypoglycemia in Patients with Type 2 Diabetes Mellitus from Korea

被引:11
作者
Kim, Gyuri [1 ,2 ]
Lee, Yong-ho [1 ]
Han, Mi Hye [3 ,4 ]
Lee, Eui-Kyung [4 ]
Kim, Chong Hwa [5 ]
Kwon, Hyuk Sang [6 ]
Jeong, In Kyung [7 ]
Kang, Eun Seok [1 ]
Kim, Dae Jung [8 ]
机构
[1] Yonsei Univ, Coll Med, Dept Internal Med, Seoul, South Korea
[2] Yonsei Univ, Coll Med, Grad Sch, Seoul, South Korea
[3] Merck Sharp & Dohme Ltd, Market Access, Seoul, South Korea
[4] Sungkyunkwan Univ, Sch Pharm, Pharmaceut Policy & Outcomes Res, Seoul, South Korea
[5] Sejong Gen Hosp, Dept Internal Med, Bucheon, South Korea
[6] Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea
[7] Kyung Hee Univ, Sch Med, Dept Internal Med, Seoul, South Korea
[8] Ajou Univ, Sch Med, Dept Endocrinol & Metab, Suwon 441749, South Korea
关键词
RISK; COMPLICATIONS; COSTS;
D O I
10.1371/journal.pone.0151282
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Hypoglycemia is a very serious complication in patients with type 2 diabetes mellitus (T2DM) and affects the economic burden of treatment. This study aims to create models of the cost of treating hypoglycemia in patients with T2DM based upon physician estimates of medical resource usage. Methods Using a literature review and personal advice from endocrinologists and emergency physicians, we developed several models for managing patients with hypoglycemia. The final model was approved by the consulting experts. We also developed 3 unique surveys to allow endocrinologists, emergency room (ER) physicians, and primary care physicians to evaluate the resource usage of patients with hypoglycemia. Medical costs were calculated by multiplying the estimated medical resource usage by the corresponding health insurance medical care costs reported in 2014. Results In total, 40 endocrinologists, 20 ER physicians, and 30 primary care physicians completed the survey. We identified 12 types of standard medical models for secondary or tertiary hospitals and 4 for primary care clinics based on the use of ER, general ward, or intensive care unit (ICU) and patients' status of consciousness and self-respiration. Estimated medical costs per person per hypoglycemic event ranged from $17.28 to $1,857.09 for secondary and tertiary hospitals. These costs were higher for patients who were unconscious and for those requiring ICU admission. Conclusion Hypoglycemia has a substantial impact on the medical costs and its prevention will result in economic benefits for T2DM patients and society.
引用
收藏
页数:11
相关论文
共 18 条
[1]   The direct medical cost of type 2 diabetes [J].
Brandle, M ;
Zhou, HH ;
Smith, BRK ;
Marriott, D ;
Burke, R ;
Tabaei, BP ;
Brown, MB ;
Herman, WH .
DIABETES CARE, 2003, 26 (08) :2300-2304
[2]   Association between hypoglycemia and inpatient mortality and length of hospital stay in hospitalized, insulin-treated patients [J].
Brodovicz, Kimberly G. ;
Mehta, Vinay ;
Zhang, Qiaoyi ;
Zhao, Changgeng ;
Davies, Michael J. ;
Chen, Jieling ;
Radican, Larry ;
Engel, Samuel S. .
CURRENT MEDICAL RESEARCH AND OPINION, 2013, 29 (02) :101-107
[3]   The progressive cost of complications in type 2 diabetes mellitus [J].
Brown, JB ;
Pedula, KL ;
Bakst, AW .
ARCHIVES OF INTERNAL MEDICINE, 1999, 159 (16) :1873-1880
[4]  
Chan Siew-Pheng, 2010, Diabetes Res Clin Pract, V89, pe30, DOI 10.1016/j.diabres.2010.05.008
[5]  
Gerstein HC, 2008, NEW ENGL J MED, V358, P2545, DOI 10.1056/NEJMoa0802743
[6]   Incidence and risk factors for severe and symptomatic hypoglycemia in type 1 diabetes. Results of the HYPOS-1 study [J].
Giorda, Carlo B. ;
Ozzello, Alessandro ;
Gentile, Sandro ;
Aglialoro, Alberto ;
Chiambretti, Anna ;
Baccetti, Fabio ;
Gentile, Francesco M. ;
Lucisano, Giuseppe ;
Nicolucci, Antonio ;
Rossi, Maria Chiara .
ACTA DIABETOLOGICA, 2015, 52 (05) :845-853
[7]   Severe Hypoglycemia Is a Serious Complication and Becoming an Economic Burden in Diabetes [J].
Ha, Won Chul ;
Oh, Su Jin ;
Kim, Ji Hyun ;
Lee, Jung Min ;
Chang, Sang Ah ;
Sohn, Tae Seo ;
Son, Hyun Shik .
DIABETES & METABOLISM JOURNAL, 2012, 36 (04) :280-284
[8]   Risk of hypoglycaemia in types 1 and 2 diabetes: effects of treatment modalities and their duration [J].
Heller, S. R. ;
Choudhary, P. ;
Davies, C. ;
Emery, C. ;
Campbell, M. J. ;
Freeman, J. ;
Amiel, S. A. ;
Malik, R. ;
Frier, B. M. ;
Allen, K. V. ;
Zammitt, N. N. ;
Macleod, K. ;
Lonnen, K. F. ;
Kerr, D. ;
Richardson, T. ;
Hunter, S. ;
Mclaughlin, D. .
DIABETOLOGIA, 2007, 50 (06) :1140-1147
[9]   Direct medical costs for patients with type 2 diabetes in Sweden [J].
Henriksson, F ;
Agardh, CD ;
Berne, C ;
Bolinder, J ;
Lönnqvist, F ;
Stenström, P ;
Östenson, CG ;
Jönsson, B .
JOURNAL OF INTERNAL MEDICINE, 2000, 248 (05) :387-396
[10]   The effect of comorbidities on risk of intensive care readmission during the same hospitalization: A linked data cohort study [J].
Ho, Kwok M. ;
Dobb, Geoffrey J. ;
Lee, Kok Y. ;
Finn, Judith ;
Knuiman, Matthew ;
Webb, Steven A. R. .
JOURNAL OF CRITICAL CARE, 2009, 24 (01) :101-107