Synthesis of spirosystems by rhodium(II)-carbenoid C-H insertion reactions.

被引：14

作者：

Aburel, PS ^{[1
]}

Undheim, K ^{[1
]}

机构：

[1] Univ Oslo, Dept Chem, N-0315 Oslo, Norway

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(98)00591-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple one-pot procedure is described for the preparation of spiro[4,4]nonane-2,7-dione derivatives from open chain bis(alpha-diazoketones). The reactions proceed by an intramolecular Rh(II)-carbenoid insertion into a methylene C-H bond yielding a cyclopentane which subsequently undergoes C-H methine insertion and cyclopentyl spiroannulation. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：3813 / 3814

页数：2

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