Malignant granular cell tumor of the vulva in a 17-year-old: Case report and literature review

被引:22
作者
Ramos, PC [1 ]
Kapp, DS
Longacre, TA
Teng, NNH
机构
[1] Stanford Univ Hosp, Dept Obstet & Gynaecol, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Dept Obstet & Gynecol, Stanford, CA 94305 USA
[3] Stanford Univ, Sch Med, Dept Radiat Oncol, Stanford, CA 94305 USA
[4] Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA
关键词
malignant granular cell tumor; prognosis; vulva;
D O I
10.1046/j.1525-1438.2000.010005429.x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Granular cell tumors are uncommon soft tissue tumors. Although the majority of these tumors are benign, a rare malignant variant exists which is aggressive, with local recurrence rates up to 70% and 3-year survival rates of less than 50%. We present a case of malignant granular cell tumor of the vulva in a 17-year-old, the sixth such case to be reported at this site. She was treated with a left hemivulvectomy and ipsilateral groin node dissection followed by postoperative radiation therapy. She remains free of disease at 16 months. Patients with malignant granular cell tumor or granular cell tumor of malignant potential are best managed with wide local excision and regional lymph node dissection.
引用
收藏
页码:429 / 434
页数:6
相关论文
共 56 条
[31]  
2-H
[32]   MALIGNANT GRANULAR-CELL TUMOR WITH INTRAPERITONEAL DISSEMINATION [J].
ODONOVAN, DG ;
KELL, P .
HISTOPATHOLOGY, 1989, 14 (04) :417-419
[33]   Granular cell tumor:: A review and update [J].
Ordóñez, NG .
ADVANCES IN ANATOMIC PATHOLOGY, 1999, 6 (04) :186-203
[34]   THE HISTOGENESIS OF GRANULAR-CELL MYOBLASTOMA (QUESTIONABLE GRANULAR-CELL PERINEURAL FIBROBLASTOMA) [J].
PEARSE, AGE .
JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1950, 62 (03) :351-&
[35]  
POWELL EB, 1946, ARCH PATHOL, V42, P517
[36]  
Pressoir R, 1980, J Natl Med Assoc, V72, P1171
[37]   MALIGNANT GRANULAR CELL MYOBLASTOMA INVOLVING THE URINARY BLADDER [J].
RAVICH, A ;
STOUT, AP ;
RAVICH, RA .
ANNALS OF SURGERY, 1945, 121 (03) :361-372
[38]   MALIGNANT GRANULAR-CELL TUMOR (MYOBLASTOMA) OF THE VULVA - REPORT OF A CASE AND REVIEW OF THE LITERATURE [J].
ROBERTSON, AJ ;
MCINTOSH, W ;
LAMONT, P ;
GUTHRIE, W .
HISTOPATHOLOGY, 1981, 5 (01) :69-79
[39]  
ROSENTHAL SA, 1990, CANCER-AM CANCER SOC, V65, P897, DOI 10.1002/1097-0142(19900215)65:4<897::AID-CNCR2820650413>3.0.CO
[40]  
2-1