Ionic liquid catalyzed solvent-free synthesis of chalcone and its derivatives under mild conditions

被引：4

作者：

Zhao, Qiu ^{[1
,2
]}

Wang, Gang ^{[2
,3
]}

Liao, Fuxia ^{[2
]}

Sha, Yifan ^{[1
]}

Xu, Fei ^{[2
]}

Li, Chunshan ^{[2
,3
]}

Li, Zengxi ^{[2
,3
]}

Cao, Yijun ^{[1
]}

机构：

[1] Zhengzhou Univ, Sch Chem Engn & Energy, Zhengzhou 450001, Peoples R China

[2] Chinese Acad Sci, State Key Lab Multiphase Complex Syst, Beijing Key Lab Ion Liquids Clean Proc, Key Lab Green Proc & Engn,Inst Proc Engn, Beijing 100190, Peoples R China

[3] Univ Chinese Acad Sci, Sch Chem Sci, Beijing 100049, Peoples R China

来源：

CHINESE JOURNAL OF CHEMICAL ENGINEERING | 2021年 / 33卷

基金：

国家自然科学基金重大项目; 中国国家自然科学基金;

关键词：

Ionic liquid; Chalcone; Aldol reaction; Kinetic model; OPTICAL-PROPERTIES; HIGH-YIELD; ONE-STEP;

D O I：

10.1016/j.cjche.2020.09.013

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

An ionic liquid (IL) catalyzed solvent-free process was developed for the direct synthesis of chalcone and its derivatives by using substituted acetophenones and benzaldehydes via aldol reaction under mild conditions. A series of acidic and basic ILs were selected and screened. The influences of cations and reaction conditions on product yield and selectivity were systematically investigated. The [Bmim]OH was identified as the optimal IL, with the highest yield and selectivity reaching up to 96.7% and 100%, respectively. A reaction mechanism-based kinetic model was established and regressed with experimental data, revealing the beta-Hydroxylketone dehydrolysis with activation barrier of 37.8 kJ.mol(-1) was observed as the rate-controlling step. (C) 2020 The Chemical Industry and Engineering Society of China, and Chemical Industry Press Co., Ltd. All righs reserved

引用

页码：160 / 166

页数：7

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