A Very Uncommon Complication Following Vaccination: Necrotizing Fasciitis and Myonecrosis: Case Report

被引:3
作者
Senaran, Hakan [1 ]
Karalezli, Nazim [1 ]
Ogun, Tunc Cevat [1 ]
机构
[1] Selcuk Univ Meram, Fac Med, Dept Orthoped & Traumatol, Konya, Turkey
来源
TURKIYE KLINIKLERI TIP BILIMLERI DERGISI | 2010年 / 30卷 / 01期
关键词
Vaccination; complications; fasciitis; necrotizing; CHILDREN; MICROBIOLOGY; CHILDHOOD; RISK;
D O I
10.5336/medsci.2008-8341
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Necrotizing fasciitis (NF) and myonecrosis is a potentially lethal soft tissue infection characterized by extensive muscular, fascial and subcutaneous tissue necrosis. In this paper, we report an 18-month-old boy admitted to a health clinic three days after Hepatitis-B vaccine injection with cellulitis at his left lateral arm and axilla. He was recommended oral antibiotics, however in the fifth day after vaccination he became lethargic, there were pseudo-paralysis, edema, crepitus on palpation and cutaneous necrosis was observed at axillary region and at posterior arm. With the diagnosis NF and myonecrosis, all the necrotic tissue including pectoralis major, triceps brachii, and most of the rotator cuff muscles were excised. After cutaneous grafting, the wounds healed, but functional recovery of the shoulder joint was poor at 4 year follow-up. Early diagnosis of NF and myonecrosis with debridment of necrotic tissue can prevent severe life threatening complications
引用
收藏
页码:384 / 386
页数:3
相关论文
共 14 条
[1]   Necrotizing fasciitis in children: Report of two cases and review of the literature [J].
Barton, LL ;
Jeck, DT ;
Vaidya, VU .
ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 1996, 150 (01) :105-108
[2]  
Birkinshaw R, 1997, J ACCID EMERG MED, V14, P52
[3]   Microbiology and management of infectious gangrene in children [J].
Brook, I .
JOURNAL OF PEDIATRIC ORTHOPAEDICS, 2004, 24 (05) :587-+
[4]   Importance of attributable risk in monitoring adverse events after immunization:: Hepatitis B vaccination in children [J].
De Serres, G ;
Duval, B ;
Boulianne, N ;
Rochette, M ;
Dionne, M ;
Fradet, MD ;
Massé, R .
AMERICAN JOURNAL OF PUBLIC HEALTH, 2001, 91 (02) :313-315
[5]  
Duclos Philippe, 2003, Expert Opin Drug Saf, V2, P225, DOI 10.1517/eods.2.3.225.21379
[6]   Major adverse reactions to yeast-derived hepatitis B vaccines - a review [J].
Grotto, I ;
Mandel, Y ;
Ephros, M ;
Ashkenazi, I ;
Shemer, J .
VACCINE, 1998, 16 (04) :329-334
[7]   Necrotizing fasciitis and myonecrosis in early childhood: a report of three patients [J].
Mordehai, J ;
Kurzbart, E ;
Cohen, Z ;
Mares, AJ .
PEDIATRIC SURGERY INTERNATIONAL, 1997, 12 (07) :538-540
[8]   Necrotizing fasciitis in children: Prompt recognition and aggressive therapy improve survival [J].
Moss, RLM ;
Musemeche, CA ;
Kosloske, AM .
JOURNAL OF PEDIATRIC SURGERY, 1996, 31 (08) :1142-1146
[9]   NECROTIZING FASCIITIS IN CHILDHOOD [J].
MURPHY, JJ ;
GRANGER, R ;
BLAIR, GK ;
MILLER, GG ;
FRASER, GC ;
MAGEE, JF .
JOURNAL OF PEDIATRIC SURGERY, 1995, 30 (08) :1131-1134
[10]   Risk factors for invasive group A streptococcal infections in children with varicella: A case-control study [J].
Peterson, CL ;
Vugia, DJ ;
Meyers, HB ;
Chao, SM ;
Vogt, J ;
Lanson, J ;
Brunell, PA ;
Kim, KS ;
Mascola, L .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1996, 15 (02) :151-156