Cortical KCNQ2/3 channels; insights from knockout mice

被引：2

作者：

Sohy, Heun ^{[1
]}

Nidayy, Zachary ^{[1
]}

Tzingounis, Anastasios V. ^{[1
]}

机构：

[1] Univ Connecticut, Dept Physiol & Neurobiol, Storrs, CT 06269 USA

来源：

CHANNELS | 2014年 / 8卷 / 05期

关键词：

Epilepsy; KCNQ2; KCNQ3; M-current; medium afterhyperpolarization; epilepsy; ACTION-POTENTIAL INITIATION; NEURONAL EXCITABILITY; SEIZURES; AXONS;

D O I：

10.4161/19336950.2014.948755

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：389 / 390

页数：2

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[31] Benign Neonatal Sleep Myoclonus: An Autosomal Dominant Form Not Allelic to KCNQ2 or KCNQ3 [J].

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[32] Distinctive mechanisms of epilepsy-causing mutants discovered by measuring S4 movement in KCNQ2 channels [J].

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[34] Functional analysis of novel KCNQ2 and KCNQ3 gene variants found in a large pedigree with benign familial neonatal convulsions (BFNC) [J].

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Vincenzo Barrese ;

Maria V. Soldovieri ;

Francesco Miceli ;

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[35] Functional analysis of novel KCNQ2 and KCNQ3 gene variants found in a large pedigree with benign familial neonatal convulsions (BFNC) [J].

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Panzeri, C ;

Piccinelli, P ;

Castaldo, P ;

Barrese, V ;

Soldovieri, MV ;

Miceli, F ;

Colombo, M ;

Bresolin, N ;

Borgatti, R ;

Taglialatela, M .

NEUROGENETICS, 2005, 6 (04) :185-193

[36] Calmodulin Activation Limits the Rate of KCNQ2 K+ Channel Exit from the Endoplasmic Reticulum [J].

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Rodriguez-Alfaro, Jose Angel ;

Areso, Pilar ;

Villarroel, Alvaro .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (31) :20668-20675

[37] M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit [J].

Tinel, N ;

Diochot, S ;

Lauritzen, I ;

Barhanin, J ;

Lazdunski, M ;

Borsotto, M .

FEBS LETTERS, 2000, 480 (2-3) :137-141

[38] Activation of muscarinic m5 receptors inhibits recombinant KCNQ2/KCNQ3 K+ channels expressed in HEK293T cells [J].

Guo, J ;

Schofield, GG .

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[39] The new KCNQ2 activator 4-Chlor-N-(6-chlor-pyridin-3-yl)-benzamid displays anticonvulsant potential [J].

Boehlen, A. ;

Schwake, M. ;

Dost, R. ;

Kunert, A. ;

Fidzinski, P. ;

Heinemann, U. ;

Gebhardt, C. .

BRITISH JOURNAL OF PHARMACOLOGY, 2013, 168 (05) :1182-1200

[40] Regulation of KCNQ2/KCNQ3 current by G protein cycling:: The kinetics of receptor-mediated signaling by Gq [J].

Suh, BC ;

Horowitz, LF ;

Hirdes, W ;

Mackie, K ;

Hille, B .

JOURNAL OF GENERAL PHYSIOLOGY, 2004, 123 (06) :663-683

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