An efficient and regiospecific synthesis of new 2,2′-bipyridine derivatives in water

An environmentally benign approach for the efficient microwave-assisted synthesis of new 2,2'-pyridine derivatives in water by the multicomponent reaction of an aldehyde, indane-1,3- dione, 2-acetylpyridine, and ammonium acetate is reported. It is an efficient and promising synthetic strategy for the construction of the 2,2'-bipyridine skeleton.